Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Bioequivalence: Overview01:16

Bioequivalence: Overview

2.2K
Pharmaceutical equivalents, by definition, are drug products with the same active ingredient in the same quantities, encapsulated in identical dosage forms, and intended for the same administration routes. These pharmaceutical equivalents are deemed bioequivalent if the bioavailability of the active entity in the drug preparations is similar. Moreover, pharmaceutical equivalents demonstrating bioequivalence are also regarded as therapeutically equivalent. This means that when used as directed,...
2.2K
Biostatistics: Overview01:20

Biostatistics: Overview

1.2K
Biostatistics plays a crucial role in understanding and analyzing data in healthcare and biology. Biostatisticians conduct experiments, gather evidence, and draw meaningful conclusions using statistical methods and techniques. Different variables form the foundation of biostatistical analysis, allowing researchers to understand and interpret data effectively. These variables are classified into different types, each serving a specific purpose in statistical analysis.
Discrete variables are...
1.2K
Health Information Technology and Healthcare Information System01:30

Health Information Technology and Healthcare Information System

1.6K
Health Information Technology (HIT)
Health Information Technology, commonly called HIT, integrates advanced information systems and technology in healthcare settings. Its primary functions include:
1.6K
Integrated Healthcare System01:20

Integrated Healthcare System

2.4K
An integrated healthcare system (IHS) is a set of organizations that provides for or arranges to provide coordinated and continuous service to a defined population. The IHS takes responsibility for that particular population's health status and outcome, both clinically and fiscally. An integrated healthcare system is a well-organized, well-coordinated, and collaborative network. The integrated delivery system is a network that connects different healthcare providers to deliver organized,...
2.4K
Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches01:23

Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches

627
Biopharmaceutical studies constitute a vital field aiming to enhance drug delivery methods and refine therapeutic approaches, drawing upon diverse interdisciplinary knowledge. In research methodologies, the choice between controlled and non-controlled studies significantly influences the study's reliability and accuracy.
Non-controlled studies, commonly employed for initial exploration, lack a control group, rendering them susceptible to biases and external influences. In contrast,...
627
Biopharmaceutics and Pharmacokinetics: Overview01:28

Biopharmaceutics and Pharmacokinetics: Overview

4.7K
Understanding drugs, drug products, and their performance in pharmaceutical science is pivotal. Drugs, whether simple molecules or complex compounds, are designed to interact with the body's biological systems to diagnose, treat, or prevent diseases. Drug products include various delivery systems such as tablets, capsules, injections, and inhalers. The performance of these drug products is gauged by their ability to deliver the active ingredient to the desired site of action at the...
4.7K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Quantifying Hallucinations in Language Language Models on Medical Textbooks.

ArXiv·2026
Same author

A Dataset and Resources for Identifying Patient Health Literacy Information from Clinical Notes.

ArXiv·2026
Same author

Overview of the ClinIQLink 2025 Shared Task on Medical Question-Answering.

ArXiv·2025
Same author

A Dataset of Medical Questions Paired with Automatically Generated Answers and Evidence-supported References.

Scientific data·2025
Same author

Comparing the efficacy of multiple quantitative and qualitative ultrasound parameters for the diagnosis of carpal tunnel syndrome.

Journal of ultrasound·2024
Same author

Candidaemia and Central Line-Associated Candidaemia in a Network of Indian ICUs: Impact of COVID-19 Pandemic.

Mycoses·2024
Same journal

Poisoning the Genome: Targeted Backdoor Attacks on DNA Foundation Models.

ArXiv·2026
Same journal

Mechanistic mathematical model of the in vitro infection dynamics of Bunyamwera and Batai viruses including MOI-dependent shortening of the eclipse phase.

ArXiv·2026
Same journal

AI-Driven Lumped-Element Modeling of Human Respiratory System for Studying Voice Mechanics.

ArXiv·2026
Same journal

Beyond Algorithms: Conceptual Innovation in Medical Imaging AI.

ArXiv·2026
Same journal

Feynman Kac Reweighted Schrödinger Bridge Matching for Surface-Based Tau PET Harmonization.

ArXiv·2026
Same journal

Agentic Discovery of Non-Canonical Antimicrobial Peptides with AMPGAN v3.

ArXiv·2026
See all related articles

Related Experiment Video

Updated: Apr 30, 2026

Evidence-based Knowledge Synthesis and Hypothesis Validation: Navigating Biomedical Knowledge Bases via Explainable AI and Agentic Systems
05:47

Evidence-based Knowledge Synthesis and Hypothesis Validation: Navigating Biomedical Knowledge Bases via Explainable AI and Agentic Systems

Published on: June 13, 2025

1.9K

BioACE: An Automated Framework for Biomedical Answer and Citation Evaluations.

Deepak Gupta1, Davis Bartels1, Dina Demner-Fushman1

  • 1Division of Intramural Research, National Library of Medicine, 8600 Rockville Pike, Bethesda, 20894, MD, USA.

Arxiv
|April 29, 2026
PubMed
Summary
This summary is machine-generated.

Evaluating answers from large language models (LLMs) in biomedicine is challenging. BioACE offers an automated framework to assess answer quality and citation accuracy, improving biomedical NLP tasks.

Keywords:
answer attributionanswer evaluationbiomedical question answering

More Related Videos

Cloud-Based Phrase Mining and Analysis of User-Defined Phrase-Category Association in Biomedical Publications
09:20

Cloud-Based Phrase Mining and Analysis of User-Defined Phrase-Category Association in Biomedical Publications

Published on: February 23, 2019

10.8K
Author Spotlight: Advancing Biotherapeutic Mass Calculation by Introducing mAbScale, a Python-Based Desktop Application
04:24

Author Spotlight: Advancing Biotherapeutic Mass Calculation by Introducing mAbScale, a Python-Based Desktop Application

Published on: June 16, 2023

2.6K

Related Experiment Videos

Last Updated: Apr 30, 2026

Evidence-based Knowledge Synthesis and Hypothesis Validation: Navigating Biomedical Knowledge Bases via Explainable AI and Agentic Systems
05:47

Evidence-based Knowledge Synthesis and Hypothesis Validation: Navigating Biomedical Knowledge Bases via Explainable AI and Agentic Systems

Published on: June 13, 2025

1.9K
Cloud-Based Phrase Mining and Analysis of User-Defined Phrase-Category Association in Biomedical Publications
09:20

Cloud-Based Phrase Mining and Analysis of User-Defined Phrase-Category Association in Biomedical Publications

Published on: February 23, 2019

10.8K
Author Spotlight: Advancing Biotherapeutic Mass Calculation by Introducing mAbScale, a Python-Based Desktop Application
04:24

Author Spotlight: Advancing Biotherapeutic Mass Calculation by Introducing mAbScale, a Python-Based Desktop Application

Published on: June 16, 2023

2.6K

Area of Science:

  • Biomedical Natural Language Processing
  • Artificial Intelligence in Healthcare
  • Scientific Literature Evaluation

Background:

  • Large language models (LLMs) are increasingly used for biomedical question answering, necessitating robust evaluation methods.
  • Evaluating LLM-generated text in the biomedical domain is complex due to specialized terminology and the need for expert scientific assessment.
  • Existing methods struggle with the nuances of biomedical text generation, including question answering and retrieval-augmented generation (RAG).

Purpose of the Study:

  • To introduce BioACE, an automated framework for evaluating biomedical answers and their supporting citations generated by LLMs.
  • To develop and validate automated metrics for assessing answer completeness, correctness, precision, and recall against ground-truth facts.
  • To compare the effectiveness of various approaches, including natural language inference (NLI) and other language models, for citation quality evaluation.

Main Methods:

  • Developed BioACE, an automated framework for biomedical answer and citation evaluation.
  • Implemented automated approaches to assess answer completeness, correctness, precision, and recall.
  • Utilized natural language inference (NLI), pre-trained language models, and LLMs to evaluate citation quality and evidence.
  • Conducted extensive experiments to correlate automated evaluations with human assessments.

Main Results:

  • The BioACE framework provides automated evaluation of biomedical answers and citations.
  • Automated metrics demonstrated correlation with human evaluations for answer quality assessment.
  • Analysis identified optimal approaches for evaluating biomedical answer and citation quality.
  • The study offers a comprehensive evaluation package for LLM-generated biomedical content.

Conclusions:

  • BioACE presents a significant advancement in the automated evaluation of LLM-generated biomedical text.
  • The framework addresses the critical need for reliable assessment of answers and citations in the biomedical domain.
  • BioACE facilitates the responsible development and deployment of LLMs for biomedical applications.
  • The findings guide the selection of best practices for biomedical answer and citation evaluation.