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Updated: May 1, 2026

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Viperin weakens IFN-I-induced immune activity by facilitating STAT1 degradation through E3 ligase UBE4A

Ying Miao1,2, Yukang Yuan1,2, Liping Qian2

  • 1Translational Clinical Immunology Key Laboratory of Sichuan Province, Department of Laboratory Medicine, Institute of Laboratory Medicine, Sichuan Provincial People's Hospital, School of Medicine, University of Electronic Science and Technology of China, Chengdu, 611731, Sichuan, China.

Cell Insight
|April 30, 2026
PubMed

Keywords:
Antiviral immunityIFN-ISTAT1UBE4AUbiquitinationViperin

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