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Updated: May 4, 2026
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Identification of Rare Bacterial Pathogens by 16S rRNA Gene Sequencing and MALDI-TOF MS
Published on: July 11, 2016
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Dysgonomonas spp. in gastrointestinal pathology
Meritxell Cubero1, Manuel Monsonís1, Noelia Muñoz1
1Microbiology Department, Hospital Sant Joan de Déu, Barcelona, Spain.
Revista Argentina De Microbiologia
|May 2, 2026
Summary
Dysgonomonas spp. can act as an opportunistic pathogen in pediatric gastroenteritis, particularly in immunocompromised children with altered gut microbiota. Further research is needed to fully understand its clinical significance.
Area of Science:
- Microbiology
- Pediatric Gastroenterology
- Infectious Diseases
Background:
- Dysgonomonas spp. is occasionally found in gastroenteritis patients, but its clinical relevance is uncertain.
- Its role is often associated with underlying conditions, especially in immunocompromised individuals.
- Further investigation is needed to clarify the exact role of Dysgonomonas spp.
Purpose of the Study:
- To investigate the pathogenesis of Dysgonomonas spp. in pediatric patients.
- To evaluate its significance in gastroenteritis and related digestive diseases.
- To link clinical context with Dysgonomonas spp. infections in children.
Main Methods:
- Retrospective and descriptive prevalence study of Dysgonomonas spp. in pediatric fecal samples (September 2019 - December 2023).
- Isolation on selective medium for Campylobacter spp., identification via MALDI-TOF, and antibiotic sensitivity testing.
- Exclusion of cases with concurrent isolation of other gastrointestinal pathogens.
Main Results:
- 45 pediatric cases (41 D. capnocitophagoides; 4 D. gadei) met inclusion criteria.
- Dysgonomonas spp. was isolated in 77.8% of gastroenteritis and 22.2% of persistent gastroenteritis cases.
- 80% of cases occurred with associated pathologies; all strains were sensitive to clindamycin and co-trimoxazole.
Conclusions:
- Dysgonomonas spp. may function as an opportunistic pathogen when intestinal microbiota is altered.
- Underlying pathologies and other factors contribute to Dysgonomonas spp. opportunistic infections.
- The study highlights the potential role of Dysgonomonas spp. in pediatric digestive issues.
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