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Reduced Itraconazole Concentration and Durations Are Successful in Treating Batrachochytrium dendrobatidis Infection in Amphibians
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In inpatients with acute-on-chronic liver failure, suspicion- vs. investigation-based antifungal therapy increased

Marwan Ghabril1, Nicolas Barros1,

  • 1Indiana University School of Medicine, Indianapolis, Indiana, USA (M.G., N.B.).

Annals of Internal Medicine
|May 4, 2026
PubMed
Abstract

Insights

This study investigates the impact of specific interventions on patient outcomes in gastroenterology and critical care settings. Findings highlight key areas for improving clinical practice and patient management.

Area of Science:

  • Gastroenterology
  • Critical Care Medicine
  • Internal Medicine

Background:

  • Gastroenterology and critical care medicine require evidence-based guidelines for optimal patient management.
  • Clinical practice variations necessitate research into effective treatment protocols.

Purpose of the Study:

  • To evaluate the clinical impact of specific interventions in gastroenterology and critical care.
  • To provide data supporting evidence-based practice in these fields.

Main Methods:

  • Systematic review and meta-analysis of relevant clinical trials.
  • Analysis of patient data from critical care and gastroenterology units.

Main Results:

  • Identified significant improvements in patient outcomes with targeted interventions.
  • Quantified the efficacy of specific treatment strategies in managing gastrointestinal and critical conditions.

Conclusions:

  • The findings support the implementation of evidence-based interventions to enhance patient care in gastroenterology and critical care.
  • Further research is recommended to refine treatment protocols and address specific clinical challenges.

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