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Selective IL-23 Inhibition in Pyoderma Gangrenosum: Promise, Questions, and Next Steps

Uwe Wollina1,2

  • 1Former Head of Department of Dermatology & Allergology, Städtisches Klinikum Dresden, Academic Teaching Hospital, Dresden, Germany.

International Journal of Dermatology
|May 5, 2026
PubMed
Abstract

No abstract available in PubMed .

Keywords:
commentaryinterleukin‐23pyoderma gangrenosumtargeted therapy

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Introduction:For diagnosing acute pyelonephritis, a comprehensive patient history is collected to identify symptoms such as dysuria, frequent or urgent urination, flank pain, or costovertebral angle (CVA) tenderness that may suggest a kidney infection.Physical ExaminationDuring the physical examination, CVA tenderness is assessed. This involves gentle percussion over the costovertebral angle, where tenderness often indicates a kidney infection.Diagnostic TestsUrinalysis: Used to identify white...

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