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Published on: November 8, 2024
Risk Factors for Venous Thromboembolism Following Surgery for Thoracolumbar Fractures.
Haseeb E Goheer1, Ramana Kolady, Phillip T Yang
1Department of Orthopaedic Surgery & Physical Performance, University of Rochester Medical Center, Rochester, New York, USA.
Male sex, anemia, heart failure, osteoporosis, and femur fractures are key risk factors for venous thromboembolism (VTE) after thoracolumbar (TL) fracture surgery. Identifying these can help prevent VTE in patients.
Area of Science:
- Orthopedic Surgery
- Vascular Surgery
- Epidemiology
Background:
- Venous thromboembolism (VTE) is a significant complication after spine surgery.
- Limited research exists on VTE risk factors specifically for thoracolumbar (TL) fractures.
Purpose of the Study:
- To identify independent risk factors for VTE within 90 days postoperatively.
- To improve VTE risk stratification in patients with TL fractures.
Main Methods:
- Retrospective cohort study using the TriNetX research database (2016-2024).
- Analysis of 4737 patients undergoing operative intervention for TL fractures.
- Multivariable logistic regression to determine independent risk factors for VTE.
Main Results:
- 4.1% of patients developed VTE postoperatively.
- Increased VTE risk associated with concurrent femur fractures, surgical complications, and major medical complications.
- Independent risk factors for VTE included male sex, preoperative anemia, congestive heart failure, osteoporosis, and femur fracture.
Conclusions:
- Male sex, preoperative anemia, congestive heart failure, osteoporosis, and femur fracture are significant independent risk factors for VTE after TL fracture surgery.
- These identified factors can aid in better risk assessment and management strategies for VTE in this patient population.
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