Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches01:23

Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches

631
Biopharmaceutical studies constitute a vital field aiming to enhance drug delivery methods and refine therapeutic approaches, drawing upon diverse interdisciplinary knowledge. In research methodologies, the choice between controlled and non-controlled studies significantly influences the study's reliability and accuracy.
Non-controlled studies, commonly employed for initial exploration, lack a control group, rendering them susceptible to biases and external influences. In contrast,...
631
Strategies for Assessing and Addressing Confounding01:25

Strategies for Assessing and Addressing Confounding

606
Confounding is a critical issue in epidemiological studies, often leading to misleading conclusions about associations between exposures and outcomes. It occurs when the relationship between the exposure and the outcome is mixed with the effects of other factors that influence the outcome. Given that, addressing confounding is of high importance for drawing accurate inferences in research.
Confounding can be addressed at both the design phase of a study and through analytical methods after data...
606
Steps in Outbreak Investigation01:18

Steps in Outbreak Investigation

780
In the ever-evolving field of public health, statistical analysis serves as a cornerstone for understanding and managing disease outbreaks. By leveraging various statistical tools, health professionals can predict potential outbreaks, analyze ongoing situations, and devise effective responses to mitigate impact. For that to happen, there are a few possible stages of the analysis:
780
Hazard Ratio01:12

Hazard Ratio

786
The hazard ratio (HR) is a widely used measure in clinical trials to compare the risk of events, such as death or disease recurrence, between two groups over time. It reflects the ratio of hazard rates—the instantaneous risk of the event occurring—between a treatment group and a control group. This measure provides valuable insights into the relative effectiveness of a treatment by assessing how the risk of an event differs between the two groups.
For example, in a clinical trial...
786
Statistical Software for Data Analysis and Clinical Trials01:12

Statistical Software for Data Analysis and Clinical Trials

1.8K
Statistical software is pivotal in data analysis and clinical trials by providing tools to analyze data, draw conclusions, and make predictions. These software packages range from simple data management applications to complex analytical platforms, supporting various statistical tests, models, and simulation techniques. Their significance lies in their ability to handle vast amounts of data with precision and efficiency, enabling researchers to validate hypotheses, identify trends, and make...
1.8K
Statistical Methods for Analyzing Epidemiological Data01:25

Statistical Methods for Analyzing Epidemiological Data

1.3K
Epidemiological data primarily involves information on specific populations' occurrence, distribution, and determinants of health and diseases. This data is crucial for understanding disease patterns and impacts, aiding public health decision-making and disease prevention strategies. The analysis of epidemiological data employs various statistical methods to interpret health-related data effectively. Here are some commonly used methods:
1.3K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Effective Strategies for Environmental Health Risk Communication.

Sustainability·2026
Same author

How Bridging Approaches Further Relationships, Governance, and Ecosystem Services Research and Practice.

Sustainability·2026
Same author

A Methodology for Designing a Roof Rainwater Quality Sensing-Recording-Grading System Using Low-Cost Sensors Paired with Microcontroller Software.

ACS ES&T water·2025
Same author

ESAT: Environmental Source Apportionment Toolkit Python package.

Journal of open source software·2025
Same author

Quantitative microbial risk assessment of pathogen exposure from rainwater used in high-pressure vehicle washing.

Journal of water and health·2025
Same author

Per- and Polyfluoroalkyl Substances: Impacts on Morphology, Behavior and Lipid Levels in Zebrafish Embryos.

Toxics·2024
Same journal

The Role of Facial Action Units in Investigating Facial Movements During Speech.

Electronics·2026
Same journal

SmartStep: A Fully Integrated, Low-Power Insole Monitor.

Electronics·2026
Same journal

A Markov Chain Replacement Strategy for Surrogate Identifiers: Minimizing Re-Identification Risk While Preserving Text Reuse.

Electronics·2025
Same journal

Evaluating Visual Dependence in Postural Stability Using Smartphone and Stroboscopic Glasses.

Electronics·2025
Same journal

Data-Driven Maturity Level Evaluation for Cardiomyocytes Derived from Human Pluripotent Stem Cells (Invited Paper).

Electronics·2025
Same journal

A Design Review for Biomedical Wireless Power Transfer Systems with a Three-Coil Inductive Link through a Case Study for NICU Applications.

Electronics·2025
See all related articles

Related Experiment Video

Updated: May 7, 2026

Demonstration of the Sequence Alignment to Predict Across Species Susceptibility Tool for Rapid Assessment of Protein Conservation
16:02

Demonstration of the Sequence Alignment to Predict Across Species Susceptibility Tool for Rapid Assessment of Protein Conservation

Published on: February 10, 2023

3.0K

Interoperability to Improve Science-Based Decision Making: Adapting a Risk Analysis Framework to Improve

John M Johnston1, Edward Perkins2, Pierre D Glynn3

  • 1US EPA Office Research and Development, Center for Environmental Measurement and Modeling, Athens, GA 30605, USA.

Electronics
|May 6, 2026
PubMed
Summary
This summary is machine-generated.

Advancing human and ecological risk assessment requires integrating diverse data and systems thinking to overcome scientific and technological challenges. This approach enhances defensible decision-making for environmental and health protection.

Keywords:
aggregate exposure pathwayautomationdata and model integrationontologies

More Related Videos

Watershed Planning within a Quantitative Scenario Analysis Framework
12:44

Watershed Planning within a Quantitative Scenario Analysis Framework

Published on: July 24, 2016

7.7K
A Protocol for Using Gene Set Enrichment Analysis to Identify the Appropriate Animal Model for Translational Research
09:35

A Protocol for Using Gene Set Enrichment Analysis to Identify the Appropriate Animal Model for Translational Research

Published on: August 16, 2017

16.6K

Related Experiment Videos

Last Updated: May 7, 2026

Demonstration of the Sequence Alignment to Predict Across Species Susceptibility Tool for Rapid Assessment of Protein Conservation
16:02

Demonstration of the Sequence Alignment to Predict Across Species Susceptibility Tool for Rapid Assessment of Protein Conservation

Published on: February 10, 2023

3.0K
Watershed Planning within a Quantitative Scenario Analysis Framework
12:44

Watershed Planning within a Quantitative Scenario Analysis Framework

Published on: July 24, 2016

7.7K
A Protocol for Using Gene Set Enrichment Analysis to Identify the Appropriate Animal Model for Translational Research
09:35

A Protocol for Using Gene Set Enrichment Analysis to Identify the Appropriate Animal Model for Translational Research

Published on: August 16, 2017

16.6K

Area of Science:

  • Environmental Science
  • Toxicology
  • Risk Assessment
  • Informatics

Background:

  • Human and ecological health protection faces increasing challenges from diverse stressors.
  • Sustainability of social, economic, and environmental systems can be improved with robust risk assessment.
  • Interoperability in data and modeling is crucial for advancing toxicology and exposure science.

Purpose of the Study:

  • To present a vision for human and ecological risk assessment using integrated data and modeling.
  • To focus on science-based decision-making where scientific evidence is the primary driver.
  • To examine barriers to systems thinking and propose recommendations for its application.

Main Methods:

  • Literature review and synthesis of current challenges in risk assessment.
  • Analysis of case studies demonstrating informatics needs for 21st-century decision-making.
  • Identification of barriers and recommendations for implementing a systems approach.

Main Results:

  • Identified scientific, technological, and cultural challenges to data interoperability and interdisciplinary integration.
  • Highlighted the need for "genome to globe" data integration and reuse of modeling approaches.
  • Examined barriers to systems thinking and proposed actionable recommendations for progress.

Conclusions:

  • A systems approach is essential for informed, science-based decision-making in risk assessment.
  • Overcoming interoperability challenges is key to leveraging "21st-century science" for health and environmental protection.
  • Implementing systems thinking requires addressing identified barriers and adopting strategic recommendations.