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Electrochemical Access to N-Aryliminium Ion Electrophiles from N-Aryl Amino Acids

Leah N White1, Fabian Dauzvardis1, Asher Chamuel1

  • 1Department of Chemistry & Biochemistry, University of Delaware, 163 The Green, Newark, Delaware 18716, United States.

The Journal of Organic Chemistry
|May 7, 2026
PubMed

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Aminolysis is a nucleophilic acyl substitution reaction, where ammonia or amines act as nucleophiles to give the substitution product. Acid halides react with ammonia, primary amines, and secondary amines to yield primary, secondary, and tertiary amides, respectively.
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