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Related Concept Videos

Drug Dosing: Obese Patients01:21

Drug Dosing: Obese Patients

In the United States, obesity is a prominent concern. It is linked to heightened mortality rates due to increased occurrences of conditions such as hypertension, atherosclerosis, coronary artery disease, and diabetes compared to nonobese individuals. A patient is classified as obese if their actual body weight surpasses the ideal or desirable body weight by 20%, based on Metropolitan Life Insurance Company data. Ideal body weights consider average weights and heights for males and females...
Obesity01:24

Obesity

The Body Mass Index (BMI) is a numerical value derived from a person's weight and height, used to categorize individuals into weight ranges. It is calculated using the formula: weight in kilograms divided by height in meters squared. Obesity is a health condition characterized by excessive accumulation of adipose tissue that poses health risks, often diagnosed with a BMI ≥ 30. This excess fat storage occurs when surplus dietary calories are converted into triglycerides and stored in adipocytes...
Diabetes: Management and Pharmacotherapy01:15

Diabetes: Management and Pharmacotherapy

The therapy for diabetes aims to alleviate hyperglycemia-related symptoms, prevent acute metabolic decompensation, and reduce chronic end-organ complications. Glycemic control is evaluated through short-term (self-monitoring, continuous glucose monitoring) and long-term (A1c, fructosamine) metrics, enabling near real-time tracking of blood glucose levels and reflecting glycemic control over specific time frames.
Insulin remains the cornerstone of treatment for most patients with type 1 and many...
Pharmacokinetics in Obese Patients: Drug Metabolism and Excretion01:20

Pharmacokinetics in Obese Patients: Drug Metabolism and Excretion

Drug metabolism, a critical process in the liver, involves two primary phases: Phase I reactions and Phase II conjugation. Obesity introduces significant alterations in this metabolic process, primarily due to fatty infiltration of the liver, leading to conditions such as nonalcoholic fatty liver disease (NAFLD). This condition can modify the activities of both Phase I and II enzymes, impacting how drugs are metabolized in obese patients.Phase I metabolism sees variable effects across...
Pharmacokinetics in Obese Patients: Drug Absorption and Distribution01:25

Pharmacokinetics in Obese Patients: Drug Absorption and Distribution

Obesity significantly alters the pharmacokinetic processes of drug absorption and distribution, presenting unique challenges in medical treatment. The increased fat tissue and decreased lean muscle in obese individuals can significantly affect how drugs are absorbed into the body and distributed across different tissues. This alteration can lead to variances in the effectiveness and safety of medications, necessitating adjustments in dosing or drug selection for obese patients.One notable...
Atherosclerosis III: Management01:26

Atherosclerosis III: Management

Management of atherosclerosis involves an integrated strategy encompassing pharmacological treatment, surgical interventions, lifestyle changes, and nutrition therapy to address the multifactorial nature of the disease.Pharmacological TherapyA cornerstone of atherosclerosis management is the use of pharmacological agents. Statins, such as atorvastatin, are pivotal in inhibiting HMG-CoA reductase, an enzyme that catalyzes an initial step in cholesterol synthesis in the liver. This reduction in...

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Related Experiment Video

Updated: May 9, 2026

Multidisciplinary Approach to Obesity Management: A Case Report
05:10

Multidisciplinary Approach to Obesity Management: A Case Report

Published on: May 30, 2025

Obesity Management: Evaluation.

A Miles Scott1, Morgan A Rhodes1, Mark Shaffer2

  • 1University of South Carolina School of Medicine; Prisma Health Family Medicine Residency Program (FMRP) in Columbia, South Carolina.

FP Essentials
|May 8, 2026
PubMed
Summary
This summary is machine-generated.

Obesity is a chronic disease affecting over 40% of US adults and 20% of children, increasing risks for numerous health issues. Recognizing it as an adiposity-based chronic disease can improve care and health equity.

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Last Updated: May 9, 2026

Multidisciplinary Approach to Obesity Management: A Case Report
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Assessment of Child Anthropometry in a Large Epidemiologic Study
09:36

Assessment of Child Anthropometry in a Large Epidemiologic Study

Published on: February 2, 2017

Area of Science:

  • Public Health
  • Chronic Disease Management
  • Health Equity

Background:

  • Obesity is a complex, multifactorial chronic condition with significant public health implications.
  • It is associated with reduced life expectancy and increased risk for cardiovascular disease, type 2 diabetes, and certain cancers.
  • Prevalence is high in the US, disproportionately affecting Hispanic and non-Hispanic Black populations and those with lower socioeconomic status.

Purpose of the Study:

  • To highlight the impact of obesity on individual and public health.
  • To discuss the definition and risk factors associated with obesity.
  • To advocate for a patient-centered approach and recognition of obesity as an adiposity-based chronic disease to improve care and reduce bias.

Main Methods:

  • Review of current definitions and statistics for obesity in adults and children.
  • Identification of contributing factors, including behavioral, genetic, and social determinants.
  • Analysis of barriers to care, such as stigma and socioeconomic factors.

Main Results:

  • Obesity affects over 40% of US adults and 20% of children and adolescents.
  • Risk factors are diverse, including adverse childhood experiences, genetics, and medical conditions.
  • Stigma and social determinants of health create significant barriers to effective management.

Conclusions:

  • Effective obesity management requires a comprehensive, patient-centered, and multidisciplinary approach.
  • Reframing obesity as an adiposity-based chronic disease can reduce bias and improve patient outcomes.
  • Addressing social determinants and stigma is crucial for promoting health equity in obesity care.