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Related Concept Videos

Blood Transfusion and Agglutination02:45

Blood Transfusion and Agglutination

Blood transfusion is a therapeutic measure to restore the blood volume after extensive blood loss due to an accident or a medical procedure. Blood transfusion involves drawing a certain amount of blood from a suitable donor and infusing it into the recipient.
History
The history of blood transfusion dates back to the 17th century, when early attempts were made in animals. In 1818 James Blundell, a British doctor, performed the first successful human blood transfusion. Later in 1900, Karl...
Blood Transfusion01:15

Blood Transfusion

Blood transfusion is a critical medical procedure that saves lives and treats various medical conditions. It involves transferring blood from a donor to a recipient. This process requires a thorough understanding of the ABO blood group system and its associated antigens and antibodies.
Blood Transfusion Overview
A blood transfusion is a medical procedure used to replace blood lost due to injury, surgery, or to treat conditions such as anemia or cancer. During a transfusion, donor blood is...
Bone Marrow Sampling and Transplants01:22

Bone Marrow Sampling and Transplants

Bone marrow transplant is a potential cure for several diseases, including cancer and specific genetic disorders. Notably, this procedure is applicable for patients suffering from aplastic anemia, certain types of leukemia, severe combined immunodeficiency disease (SCID), Hodgkin's disease, non-Hodgkin's lymphoma, multiple myeloma, thalassemia, sickle-cell disease, and certain cancers.
The transplant begins with high doses of chemotherapy and radiation treatment, which aim to destroy the...
Tissue Transplantation01:24

Tissue Transplantation

Tissue transplantation is a significant medical procedure involving the transfer of cells, tissues, or organs from a donor to a recipient, with the primary aim of restoring lost functions. This procedure is crucial in treating a broad spectrum of diseases, including kidney diseases, liver failure, heart disease, and certain types of cancers.
The Biology of Tissue Transplantation
The biology of tissue transplantation hinges on the Major Histocompatibility Complex (MHC) molecules. These molecules...
Kidney Transplant I: Introduction01:28

Kidney Transplant I: Introduction

A kidney transplant is a surgical approach that involves replacing a non-functioning kidney with a healthy one from a donor. This procedure is often a treatment option for end-stage renal disease (ESRD) patients. The method requires careful recipient selection, including evaluating various medical and psychosocial factors. These criteria vary between transplant centers but generally include assessments of the patient's overall health, adherence to medical recommendations, and lifestyle...
Heart Failure VI: Adjunct Therapies01:22

Heart Failure VI: Adjunct Therapies

Additional therapies for treating patients with heart failure (HF) may include procedural interventions, supplemental oxygen, the management of sleep disorders, and nutritional therapy.Procedural InterventionsImplantable Cardioverter-Defibrillator: For patients at risk of life-threatening arrhythmias due to severe left ventricular dysfunction, an Implantable Cardioverter-Defibrillator (ICD) can detect and terminate these arrhythmias, preventing sudden cardiac death and improving survival rates.

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Related Experiment Video

Updated: May 13, 2026

Continuous Manual Exchange Transfusion for Patients with Sickle Cell Disease: An Efficient Method to Avoid Iron Overload
05:23

Continuous Manual Exchange Transfusion for Patients with Sickle Cell Disease: An Efficient Method to Avoid Iron Overload

Published on: March 14, 2017

Blood Transfusion Practices in Rural Hospitals: Indications, Challenges, and Practical Solutions.

Vijay Ramesh Topno1, Ghanshyam Bihari2, Gaurav Mishra3

  • 1Department of Pathology, Tata Main Hospital, Noamundi, IND.

Cureus
|May 12, 2026
PubMed
Summary
This summary is machine-generated.

Safe blood transfusion (BT) in rural areas requires integrated systems focusing on supply resilience and workforce training. Prioritizing physiological criteria over delayed lab results improves urgent care, enhancing patient blood management (PBM) and reducing transfusion-transmitted infections (TTIs).

Keywords:
blood transfusioncold chainpatient blood managementrural hospitalstransfusion safety

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A Point-of-Care Method with Integrated Decision Support Tool to Estimate Anemia at Population Level
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A Point-of-Care Method with Integrated Decision Support Tool to Estimate Anemia at Population Level

Published on: January 19, 2024

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Last Updated: May 13, 2026

Continuous Manual Exchange Transfusion for Patients with Sickle Cell Disease: An Efficient Method to Avoid Iron Overload
05:23

Continuous Manual Exchange Transfusion for Patients with Sickle Cell Disease: An Efficient Method to Avoid Iron Overload

Published on: March 14, 2017

A Point-of-Care Method with Integrated Decision Support Tool to Estimate Anemia at Population Level
05:35

A Point-of-Care Method with Integrated Decision Support Tool to Estimate Anemia at Population Level

Published on: January 19, 2024

Area of Science:

  • Medical Science
  • Public Health
  • Healthcare Management

Background:

  • Blood transfusion (BT) and red blood cell (RBC) transfusion are critical in healthcare, especially in resource-limited settings facing access, safety, and logistical challenges.
  • Transfusion-transmitted infections (TTIs) and diagnostic delays pose significant risks, highlighting evidence gaps in patient blood management (PBM).

Purpose of the Study:

  • To synthesize blood transfusion indications, operational challenges, and practical solutions for decentralized and remote hospital environments.
  • To address evidence gaps in TTI testing costs, surveillance, and diagnostic delays impacting transfusion decisions.

Main Methods:

  • A structured literature synthesis was performed using PubMed, Scopus, and Google Scholar.
  • Searched for studies published between 2015 and 2025 on BT practices, rural healthcare, and transfusion safety in resource-limited settings.

Main Results:

  • Key outcomes include transfusion thresholds in hemoglobinopathies and sepsis, feasibility of universal-donor products in trauma, and cold-chain integrity.
  • Prioritizing physiological criteria for urgent BT when lab access is delayed is crucial.
  • Integrated transfusion pathways combining decentralized preparedness with pathogen screening and monitoring are supported.

Conclusions:

  • Safe rural blood transfusion systems necessitate coordinated investment in supply resilience, workforce competency, and technology-enabled verification.
  • Strengthening governance through clinical audits and point-of-care electronic verification is recommended.
  • Relying on isolated interventions is insufficient; integrated approaches are essential for safe rural BT.