Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Inflammatory Bowel Disease V: Surgical Management01:21

Inflammatory Bowel Disease V: Surgical Management

Surgical interventions for inflammatory bowel disease (IBD), which includes ulcerative colitis and Crohn's disease, are essential in managing symptoms and addressing complications. The selection of surgical procedures is contingent upon the specific conditions and complications that stem from these illnesses.
Here are some common surgical interventions for IBD:
Tissue Transplantation01:24

Tissue Transplantation

Tissue transplantation is a significant medical procedure involving the transfer of cells, tissues, or organs from a donor to a recipient, with the primary aim of restoring lost functions. This procedure is crucial in treating a broad spectrum of diseases, including kidney diseases, liver failure, heart disease, and certain types of cancers.
The Biology of Tissue Transplantation
The biology of tissue transplantation hinges on the Major Histocompatibility Complex (MHC) molecules. These molecules...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Microsurgical education for medical students: systematic review.

Acta cirurgica brasileira·2026
Same author

Second Report of the American Intestinal Transplant Working Group: New Insights Into Risk Factors, Treatment Regimens, and Outcomes of Malignancy After Intestinal Transplantation.

Transplantation·2026
Same author

Temporal analysis of intraoperative arterial thrombosis: Validation of a 20-min patency check.

Journal of plastic, reconstructive & aesthetic surgery : JPRAS·2026
Same author

Successful Pregnancy and Delivery Following Autologous Abdominal Wall Reconstruction: A Case Report and Literature Review.

Plastic and reconstructive surgery. Global open·2026
Same author

Temporoparietal Fascia and Temporalis Muscle Flaps for External Auditory Canal Reconstruction After Tumor Resection.

The Journal of craniofacial surgery·2026
Same author

Safety and utility of subcutaneous gadobutrol-enhanced MR lymphography for preoperative mapping in lymphovenous anastomosis: A phase II trial.

Journal of plastic, reconstructive & aesthetic surgery : JPRAS·2026
Same journal

Efficacy of Ninjin'yoeito in Adjuvant Chemotherapy for Colorectal Cancer: A Retrospective Clinical Study with Propensity Score Matching Analysis.

Journal of the anus, rectum and colon·2026
Same journal

Preoperative and Pathological Discrepancies in Colorectal Cancer: A Single-Institution Retrospective Analysis Based on Mismatch Repair/<i>BRAF</i> V600E Status.

Journal of the anus, rectum and colon·2026
Same journal

Experience with hinotori<sup>TM</sup>, the Japan-made Surgical Robotic System, in the Initial 94 Cases of Colorectal Cancer.

Journal of the anus, rectum and colon·2026
Same journal

Identifying High-risk Patients with Synchronous Colorectal Liver Metastasis: Implications for Preoperative Chemotherapy Selection.

Journal of the anus, rectum and colon·2026
Same journal

Erratum for Transanal Decompression Tube Placement for Treatment of Sigmoid Volvulus.

Journal of the anus, rectum and colon·2026
Same journal

Simultaneous Resection of Rectal and Gastric Cancer with the da Vinci Single-Port System: A Case Report.

Journal of the anus, rectum and colon·2026
See all related articles

Related Experiment Video

Updated: May 14, 2026

Orthotopic Small Bowel Transplantation in Rats
09:16

Orthotopic Small Bowel Transplantation in Rats

Published on: November 6, 2012

Anorectal Transplantation: Current Overview and Translational Perspectives.

Julia Belotto Guaraná1, Silvio Henrique de Freitas1, Cinthia Lanchotte2

  • 1Department of Veterinary Medicine, Faculdade de Zootecnica e Engenharia de Alimentos (FZEA), Universidade de São Paulo, São Paulo, Brazil.

Journal of the Anus, Rectum and Colon
|May 13, 2026
PubMed
Summary
This summary is machine-generated.

Anorectal transplantation (ART) shows promise for restoring anal function in patients with severe fecal incontinence and permanent colostomy. Experimental studies confirm technical feasibility, graft viability, and functional restoration, paving the way for clinical application.

Keywords:
anal dysfunctionanorectal functionfecal incontinencepermanent colostomytransplantation

More Related Videos

Small Bowel Transplantation In Mice
36:30

Small Bowel Transplantation In Mice

Published on: August 20, 2007

A Rat Graft Rejection Model of Intestinal Transplantation with Exteriorized Ileostomy for Longitudinal Prognosis Assessment
08:25

A Rat Graft Rejection Model of Intestinal Transplantation with Exteriorized Ileostomy for Longitudinal Prognosis Assessment

Published on: June 10, 2025

Related Experiment Videos

Last Updated: May 14, 2026

Orthotopic Small Bowel Transplantation in Rats
09:16

Orthotopic Small Bowel Transplantation in Rats

Published on: November 6, 2012

Small Bowel Transplantation In Mice
36:30

Small Bowel Transplantation In Mice

Published on: August 20, 2007

A Rat Graft Rejection Model of Intestinal Transplantation with Exteriorized Ileostomy for Longitudinal Prognosis Assessment
08:25

A Rat Graft Rejection Model of Intestinal Transplantation with Exteriorized Ileostomy for Longitudinal Prognosis Assessment

Published on: June 10, 2025

Area of Science:

  • Vascularized Composite Allotransplantation (VCA)
  • Surgical Innovation
  • Regenerative Medicine

Background:

  • Severe fecal incontinence and permanent colostomy significantly impair quality of life.
  • These conditions represent a global public health challenge.
  • Current treatment options are limited for irreversible anorectal dysfunction.

Purpose of the Study:

  • To conduct a comprehensive narrative review of anorectal transplantation (ART) research.
  • To analyze experimental studies in animal models and ex vivo investigations.
  • To evaluate surgical techniques, procedural effectiveness, and functional recovery in ART.

Main Methods:

  • Review of experimental studies on anorectal transplantation.
  • Analysis of ex vivo investigations and animal model studies.
  • Comparison of different surgical techniques and outcomes.

Main Results:

  • Anorectal transplantation is technically feasible.
  • Ex vivo studies show acceptable surgical times.
  • Animal models confirm graft viability and functional restoration.

Conclusions:

  • ART demonstrates potential for treating severe anorectal dysfunction and permanent colostomy.
  • Further research is needed to refine surgical techniques and immunosuppression.
  • Advancing ART could offer a definitive solution for patients with irreversible conditions.