Dehydration-Induced Motional Heterogeneity in Native Collagen Protein Probed by Solid-State NMR Spectroscopy.

Bijaylaxmi Patra1,2, Neeraj Sinha1,2

  • 1Centre of Biomedical Research, SGPGIMS Campus, Raebareli Road, Lucknow 226014, India.

Biomacromolecules
|May 13, 2026
PubMed
Summary

Dehydration significantly alters collagen dynamics in bone extracellular matrix by restricting molecular motion. This study reveals how water loss impacts specific collagen components, offering insights into protein structure and function.

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