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Updated: May 17, 2026

Improving IV Insulin Administration in a Community Hospital
Published on: June 11, 2012
Development of a protocol on safe practices for insulin preparation and administration
Tatiana Rebouças Moreira1, Rhanna Emanuela Fontenele Lima de Carvalho1, Consuelo Helena Aires de Freitas1
1Universidade Estadual do Ceará. Fortaleza, Ceará, Brazil.
Objectives:
to develop and validate a protocol for safe insulin preparation and administration in healthcare settings.
Methods:
this methodological study, conducted from September 2022 to May 2024, had two phases. Phase one involved protocol development and validity by 46 experts using AGREE II for content and methodological aspects. Phase two trained 40 healthcare professionals in Fortaleza, Brazil, with pre/post-tests assessing knowledge acquisition. Data were analyzed using descriptive statistics, reproducibility measures (Cronbach's alpha, McDonald's omega), Content Validity Index, and various statistical tests.
Results:
the protocol achieved high quality and internal consistency, with a Content Validity Index of 97.83-100 (p<0.001). Its overall quality score was 95.7% (6.70 ± 0.47), and all six domains scored ≥ 90.0. High reproducibility was confirmed (alpha=0.94, omega=0.95). After training, correct responses significantly increased from 32% to 70%.
Conclusions:
the validated protocol is a high-quality technology that significantly enhances healthcare professionals' knowledge of safe insulin practices.
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