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Related Concept Videos

Ultrasonography01:17

Ultrasonography

Ultrasonography is an imaging technique that uses high-frequency sound waves to visualize the body's internal structures. It is a non-invasive and safe procedure that does not involve the use of ionizing radiation, making it widely used in various medical fields. Ultrasonography is used to study heart function, blood flow in the neck or extremities, certain conditions such as gallbladder disease, and fetal growth and development.
During an ultrasonography procedure, a handheld device called a...
Imaging Studies II: Ultrasonography01:24

Imaging Studies II: Ultrasonography

IntroductionUltrasonography, or renal ultrasound, is a noninvasive medical imaging technique that uses high-frequency sound waves to visualize the kidneys, ureters, bladder, and surrounding tissues.Indications for Urinary System UltrasonographyUrinary system ultrasonography is indicated in various clinical scenarios, such as:Kidney Stones (Urolithiasis): To detect and monitor the size and presence of kidney or urinary tract stones.Hydronephrosis: To assess the dilation of the renal pelvis and...
Ultrasound I: Abdominal Ultrasonography01:20

Ultrasound I: Abdominal Ultrasonography

Introduction:
Abdominal ultrasonography, commonly known as abdominal ultrasound, is a vital, non-invasive medical imaging technique widely used in healthcare.
Procedure:
This diagnostic tool allows the clinician to visually inspect internal structures within the abdomen, including vital organs such as the liver, gallbladder, pancreas, kidneys, and spleen.
The abdominal ultrasound process begins with applying a special gel to the patient's skin over the abdomen. This gel enhances the...

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Related Experiment Video

Updated: May 19, 2026

Contrast Imaging in Mouse Embryos Using High-frequency Ultrasound
10:39

Contrast Imaging in Mouse Embryos Using High-frequency Ultrasound

Published on: March 4, 2015

Molecular Ultrasound Imaging.

Anne Rix1, Jasmin Baier1, Fabian Kiessling2

  • 1Institute for Experimental Molecular Imaging, University Hospital, RWTH Aachen University, Northrhein-Westphalia, Germany.

Recent Results in Cancer Research. Fortschritte Der Krebsforschung. Progres Dans Les Recherches Sur Le Cancer
|May 18, 2026
PubMed
Summary
This summary is machine-generated.

Molecular contrast-enhanced ultrasound (CEUS) uses targeted microbubbles to detect cancer markers like VEGFR2. Early clinical trials show promising safety and tumor detection in prostate, breast, and ovarian cancers.

Keywords:
Active targetingBR55CEUSImagingIntegrinUltrasound imagingVEGFR2microbubble

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Last Updated: May 19, 2026

Contrast Imaging in Mouse Embryos Using High-frequency Ultrasound
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Area of Science:

  • Medical imaging
  • Nanotechnology
  • Oncology

Background:

  • Contrast-enhanced ultrasound (CEUS) is a key diagnostic tool.
  • Microbubbles are common ultrasound contrast agents.
  • Novel nanomaterials are being explored for CEUS applications.

Purpose of the Study:

  • To explore molecular CEUS for targeted disease detection.
  • To investigate ultrasound contrast agents targeting cancer markers.
  • To evaluate the potential of molecular ultrasound in oncology.

Main Methods:

  • Modification of ultrasound contrast agents with ligands for molecular targeting.
  • Utilizing agents targeting neoangiogenesis markers like VEGFR2 and αvβ3-Integrin.
  • Application in preclinical and clinical settings for tumor imaging.

Main Results:

  • Molecular CEUS enables longitudinal monitoring of receptor expression during tumor growth.
  • It effectively detects neovascularization and evaluates therapy responses.
  • First clinical trials with VEGFR2-targeted microbubbles show safety and tumor detection in prostate, breast, and ovarian cancers.

Conclusions:

  • Molecular CEUS is a safe and effective method for tumor detection.
  • Targeted ultrasound contrast agents show potential for improved cancer diagnostics.
  • Future applications include ultrasound theranostics for enhanced drug delivery.