Related Experiment Video
Updated: May 20, 2026
08:52
Intravital Microscopy of Tumor-associated Vasculature Using Advanced Dorsal Skinfold Window Chambers on Transgenic Fluorescent Mice
Published on: January 19, 2018
Multifaceted Modulation of Tumor Microenvironment Dynamics: Emerging Cross-Disciplinary Paradigms in Precision Drug
Sakshi Soni1, Sunny Rathee1,2, Umesh K Patil1
1Department of Pharmaceutical Sciences, Dr. Harisingh Gour Vishwavidyalaya, (A Central University), Sagar, Madhya Pradesh, 470003, India.
Current Pharmaceutical Design
|May 19, 2026
Summary
Artificial intelligence and materials science are revolutionizing cancer therapy by enabling personalized treatments. These advancements target the tumor microenvironment (TME) for improved drug delivery and reduced toxicity.
Area of Science:
- Interdisciplinary research integrating artificial intelligence, cancer biology, and materials science.
Background:
- Cancer remains a major global health challenge, necessitating innovative therapeutic approaches.
- The tumor microenvironment (TME) is a complex system influencing cancer progression and drug resistance.
Purpose of the Study:
- To review the impact of artificial intelligence (AI) and materials science on modern cancer therapies.
- To explore how AI and advanced materials enhance understanding and treatment of the TME.
Main Methods:
- AI integration with omics data, medical imaging, and clinical information for TME analysis.
- Development of smart drug delivery systems responding to tumor-specific or external stimuli.
- Utilizing ligand-mediated targeting strategies and AI for nanoparticle-based therapies.
Main Results:
- AI aids in understanding the TME, identifying drug targets, and predicting treatment response.
- Materials science enables targeted and stimuli-responsive drug delivery systems.
- Integration of AI and precision delivery improves drug accumulation at tumor sites and minimizes systemic toxicity.
Conclusions:
- AI and biomaterials advancements are driving personalized cancer treatment strategies.
- Further integration promises improved cancer therapy by overcoming TME barriers.
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