Copper-Catalyzed Remote Asymmetric Three-Component Sulfonylation Using SO2 as the Sulfur Source to Access Chiral

Jiale Li1, Wenli Yan1, Shuning Liu2

  • 1Shanghai Key Laboratory of Functional Materials Chemistry, Key Laboratory for Advanced Materials, School of Chemistry and Molecular Engineering, East China University of Science & Technology, Shanghai 200237, China.

Organic Letters
|May 19, 2026
PubMed
Summary

A novel copper-catalyzed reaction efficiently synthesizes chiral allylic sulfones from simple precursors. This method offers high enantioselectivity and broad functional group tolerance under mild conditions.

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