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Characterization of Leukocyte-platelet Rich Fibrin, A Novel Biomaterial
Published on: September 29, 2015
Platelet-Rich Fibrin (PRF) Application and Education in US Graduate Programs: A Cross-Sectional Study
Elena Furman1, Mark Piroutek2, T Roma Jasinevicius3
1Department of Periodontics, Case Western Reserve University - School of Dental Medicine, Cleveland, Ohio, USA.
Journal of Dental Education
|May 20, 2026
Summary
Platelet-rich fibrin (PRF) is widely used in periodontology and oral surgery training programs in the US. However, significant variability exists in its application, training, and equipment, highlighting a need for standardization in dental education.
Area of Science:
- Biomaterials Science
- Dental Education
- Regenerative Medicine
Background:
- Platelet-rich fibrin (PRF) is a bioactive wound healing material derived from autologous blood.
- Its application in dentistry, particularly in regenerative procedures, is growing.
- Understanding its integration into graduate dental education is crucial for future practice.
Purpose of the Study:
- To assess the current application and educational practices of platelet-rich fibrin (PRF) in US graduate periodontology, endodontics, and oral and maxillofacial surgery programs.
- To identify barriers to PRF implementation and training.
Main Methods:
- A cross-sectional survey was electronically distributed to program directors in periodontology, endodontics, and oral and maxillofacial surgery (OMFS) programs across the US.
- The survey focused on PRF implementation, equipment, procedures, and educational components.
- Data were analyzed using descriptive statistics and Fisher's exact test.
Main Results:
- A 31% response rate (55/176) was achieved.
- PRF use was high in periodontology (100%) and OMFS (65%) programs, but low in endodontics (19%).
- Most programs (71%) provided didactic and clinical training, typically 1-5 hours.
- Bone grafting was the most common PRF application (97%).
- Lack of equipment availability was the primary barrier for non-implementing programs.
Conclusions:
- Most graduate periodontology and OMFS programs utilize PRF and provide resident training.
- Significant variability exists in PRF application, training methods, duration, equipment, and outcome evaluation.
- Standardization is needed to optimize PRF integration into dental education and clinical practice.
