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Updated: May 22, 2026

Lumped-Parameter and Finite Element Modeling of Heart Failure with Preserved Ejection Fraction
Published on: February 13, 2021
A synergistic framework for hemodynamics within eccentric vascular constrictions
1Department of Mathematics, University of Gujrat, Gujrat, Pakistan.
Abstract:
This study analyzes blood flow hemodynamics within tilted ellipsoidal stenosed arteries. Modeling blood as a non-Newtonian fluid via the Carreau model, we evaluate the impact of zero shear rate viscosity and relaxation time on flow fields. Solutions obtained using the finite element method in COMSOL Multiphysics are validated against the Homotopy Perturbation Method. Simulations under severe pathological conditions (μ0 = 0.076 Pa·s) reveal critical flow dampening, with peak axial velocities of 0.14-0.22 m/s. This disturbed flow causes a substantial 15,400 Pa pressure drop. The findings highlight the necessity of advanced rheological models for accurate arterial disease prediction.
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