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Mapping the Genetics of Snoring: Insights into Family Patterns
Sunil Kumar Kadiri1, Prashant Tiwari1
1Department of Pharmacology, College of Pharmaceutical Sciences, Dayananda Sagar University, Harohalli, Bengaluru South, Karnataka- 562112, India.
Abstract:
Snoring is an everyday sleep phenomenon that impacts the overall health and quality of life. This review article describes the complex interplay of genetic and familial factors in snoring behavior. The discussion begins by reviewing the anatomical and physiological basis of snoring, with particular consideration of how genetic factors may affect the shaping of the upper airway. The article explores several studies proving that snoring can be inherited, exposing family case studies that reveal the patterns of recurrence. This review focuses on the detection of certain gene-related markers of snoring and the role of exogenous factors, such as obesity and habits of living, that may intensify genetic predisposition. The analysis illustrates the importance of assessing the genetic risk and the potential of genetic counseling in familial snoring. The prospective lines of investigation to further understand the genetic basis of snoring and the implications for tailored therapeutic approaches have been underlined. This contribution aims to clarify the genetic underpinnings of snoring and to facilitate further research into its hereditary potential by synthesising current findings for interested readers. Genetic research has shown that snoring is associated with heritable traits related to the structure of the airway, muscle tone, and the distribution of fat. Technologies such as next-generation sequencing and CRISPR enable the identification of genetic variants for targeted therapeutic intervention. Genetic-based treatments are more effective, and this has led to a paradigm change in sleep care with personalized approaches to snoring management.
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