Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Acute Respiratory Failure-II01:21

Acute Respiratory Failure-II

Type I Respiratory Failure, or hypoxemic respiratory failure, occurs when the partial pressure of oxygen (PaO2) in arterial blood falls below 60 mmHg while breathing room air without a corresponding increase in arterial carbon dioxide levels (PaCO2). This condition highlights a significant impairment in the lungs' capacity to oxygenate the blood.
The underlying physiological abnormalities that contribute to hypoxemic respiratory failure include:
Pneumothorax-II01:27

Pneumothorax-II

Pneumothorax is a medical condition defined by the buildup of air in the pleural space between the lungs and the chest wall. This accumulation of air can lead to partial or complete lung collapse, resulting in a range of clinical manifestations. Understanding the clinical presentation and effective management strategies is crucial for healthcare professionals in providing timely and appropriate care to individuals with pneumothorax.
Clinical Manifestations:
Pneumothorax-I01:26

Pneumothorax-I

A pneumothorax is a condition where air builds up in the space between the lung and the chest wall, causing the lung to collapse. This condition arises when air enters the space between the parietal and visceral pleura, disrupting the negative pressure essential for lung inflation. This can lead to a partial or complete collapse of the lung.
Pneumothorax can be even further classified as spontaneous, traumatic, and tension pneumothorax.
Oxygen Delivering System II: Venturi Mask and Transtracheal Oxygen01:16

Oxygen Delivering System II: Venturi Mask and Transtracheal Oxygen

Oxygen therapy is a pivotal aspect of medical care, particularly for patients with respiratory ailments. Two prominent oxygen-delivering systems include the Venturi mask and the transtracheal oxygen catheter.
Venturi Mask
The Venturi mask, named after the Venturi effect, is designed to deliver precise oxygen concentrations. It consists of a large tube with an oxygen inlet that narrows down, causing a pressure drop that pulls air in through adjustable side ports. The mask is a lightweight,...
Mitral Stenosis I: Introduction01:22

Mitral Stenosis I: Introduction

Mitral Valve Stenosis (MVS) is a heart condition where the mitral valve narrows, impeding blood circulation from the left atrium to the left ventricle. The etiology and pathophysiology of this condition are multifaceted, leading to a cascade of cardiovascular complications.Causes of Mitral Valve StenosisRheumatic Heart Disease: It is the main cause of mitral valve stenosis, particularly in developing nations. This condition arises from rheumatic fever, an inflammatory illness resulting from...
Acute Respiratory Failure-III01:30

Acute Respiratory Failure-III

Hypercapnic respiratory failure, also known as Type 2 or ventilatory respiratory failure, is a severe condition characterized by the body's inability to effectively remove carbon dioxide (CO2) from the bloodstream. It leads to an arterial CO2 pressure (PaCO2) exceeding 45 mmHg and a blood pH above 7.35. This situation indicates that the body's ventilatory demand, or the ventilation needed to maintain normal PaCO2 levels, surpasses its supply or the maximum gas flow achievable without causing...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Patient-derived organoids across cancers reveal conserved tumor heterogeneity and actionable therapeutic vulnerabilities.

Science advances·2026
Same author

Pharmacokinetics of xylazine and fentanyl in patients presenting to the emergency department after non-fatal opioid overdose.

Drug and alcohol dependence·2026
Same author

Very low-carbohydrate ketogenic diet in treatment-naïve women with endometrial cancer and overweight: a randomized feasibility study.

Nature communications·2026
Same author

Social Context Considerations for Future HIV Vaccine Introduction and Implementation.

Vaccines·2026
Same author

Tumor immune microenvironment reconstitution in patient-derived organoids enables therapy modeling for NSCLC.

Cell reports methods·2026
Same author

Safety and efficacy of bilateral same-day optic nerve sheath fenestration.

Orbit (Amsterdam, Netherlands)·2026
Same journal

Atrioventricular Block Induced by Right Coronary Artery Spasm in Vasospastic Angina.

JACC. Case reports·2026
Same journal

Balloon Sizing-Guided Valve Selection for Transcatheter Aortic Valve Replacement in Bicuspid Aortic Valve.

JACC. Case reports·2026
Same journal

Giant Pulmonary Artery Aneurysm in Chronic Thromboembolic Pulmonary Hypertension: Multimodality Imaging of a Rare Complication.

JACC. Case reports·2026
Same journal

Left Atrial Appendage Aneurysm and Atrial Fibrillation: A Case Report of Surgical Resection and Ablation.

JACC. Case reports·2026
Same journal

A Bailout Multiwire Technique for Retrieval of a Deployed Coronary Stent Entrapping a Guidewire.

JACC. Case reports·2026
Same journal

Traumatic Coronary Artery Dissection Treated With Prolonged Perfusion Balloon Inflation.

JACC. Case reports·2026
See all related articles

Related Experiment Video

Updated: May 22, 2026

Chronic Ovine Model of Right Ventricular Failure and Functional Tricuspid Regurgitation
08:43

Chronic Ovine Model of Right Ventricular Failure and Functional Tricuspid Regurgitation

Published on: March 17, 2023

Persistent Hypoxia After Tricuspid Valve Replacement.

John Nguyen1, Thomas Merino2, Vijay Kandula1

  • 1Texas A&M College of Medicine, Baylor Scott & White Medical Center-Round Rock, Round Rock, Texas, USA.

JACC. Case Reports
|May 21, 2026
PubMed
Summary
This summary is machine-generated.

Transcatheter tricuspid valve replacement (TTVR) can cause platypnea-orthodeoxia syndrome due to right atrial changes and shunting through a patent foramen ovale (PFO). Percutaneous PFO closure effectively resolves this complication.

Area of Science:

  • Cardiology
  • Interventional Cardiology
  • Cardiac Surgery

Background:

  • Transcatheter tricuspid valve replacement (TTVR) is an emerging treatment for severe tricuspid regurgitation in high-risk patients.
Keywords:
PFOTRTTVRanatomic distortioninteratrial communicationpercutaneous device closureplatypnea-orthodeoxia syndromeshunting

More Related Videos

Cox-Maze IV Procedure Concomitant with Valvular Surgery In Situs Inversus Dextrocardia: A Single-Center Experience in China
08:42

Cox-Maze IV Procedure Concomitant with Valvular Surgery In Situs Inversus Dextrocardia: A Single-Center Experience in China

Published on: February 11, 2022

Related Experiment Videos

Last Updated: May 22, 2026

Chronic Ovine Model of Right Ventricular Failure and Functional Tricuspid Regurgitation
08:43

Chronic Ovine Model of Right Ventricular Failure and Functional Tricuspid Regurgitation

Published on: March 17, 2023

Cox-Maze IV Procedure Concomitant with Valvular Surgery In Situs Inversus Dextrocardia: A Single-Center Experience in China
08:42

Cox-Maze IV Procedure Concomitant with Valvular Surgery In Situs Inversus Dextrocardia: A Single-Center Experience in China

Published on: February 11, 2022

  • Platypnea-orthodeoxia syndrome is a rare but serious complication not previously associated with TTVR.