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Related Concept Videos

Positron Emission Tomography01:29

Positron Emission Tomography

Positron emission tomography (PET) is a medical imaging technique involving radiopharmaceuticals — substances that emit short-lived radiation. Although the first PET scanner was introduced in 1961, it took 15 more years before radiopharmaceuticals were combined with the technique and revolutionized its potential.
One of the main requirements of a PET scan is a positron-emitting radioisotope, which is produced in a cyclotron and then attached to a substance used by the part of the body being...
Imaging Studies II: Positron Emission Tomography and Scintigraphy01:25

Imaging Studies II: Positron Emission Tomography and Scintigraphy

Positron Emission Tomography (PET) is a medical imaging technique that provides crucial insights into the body's physiological functions at a molecular level. It is an indispensable resource for diagnosing, staging, and monitoring various illnesses, notably cancer, neurological disorders, and cardiovascular conditions.
Fundamental Principles of PET
Radiological Investigation III: Pulmonary Angiogram and PET Scan01:13

Radiological Investigation III: Pulmonary Angiogram and PET Scan

Radiological investigations are paramount in the diagnosis and management of various pulmonary diseases. Two essential investigations are the Pulmonary Angiogram and the Positron Emission Tomography (PET) Scan.
Pulmonary Angiogram
A Pulmonary Angiogram is an invasive procedure involving injecting a contrast medium through a catheter threaded into the pulmonary artery or the right side of the heart to visualize the pulmonary vasculature. Computed Tomography (CT) scans have mainly replaced this...

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Functional Imaging of Brown Fat in Mice with 18F-FDG micro-PET/CT
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Functional Imaging of Brown Fat in Mice with 18F-FDG micro-PET/CT

Published on: November 23, 2012

FDG PET Hybrid Imaging.

Caner Civan1, Wolfgang P Fendler2, Bernd J Krause3

  • 1Department of Nuclear Medicine, DKTK and NCT University Hospital Essen, Essen, Germany. caner.civan@ext.uk-essen.de.

Recent Results in Cancer Research. Fortschritte Der Krebsforschung. Progres Dans Les Recherches Sur Le Cancer
|May 21, 2026
PubMed
Summary
This summary is machine-generated.

Positron emission tomography/computed tomography (PET/CT) is a vital tool in oncology for diagnosing, staging, and monitoring various cancers. This imaging technique, particularly using 18-F-fluorodeoxyglucose (FDG), aids in treatment planning and evaluating therapeutic response.

Keywords:
FDGHybrid imagingOncologyPET/CTRestagingStagingTherapy response assessment

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Gene Regulation and Targeted Therapy in Gastric Cancer Peritoneal Metastasis: Radiological Findings from Dual Energy CT and PET/CT
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Utilizing 18F-FDG PET/CT Imaging and Quantitative Histology to Measure Dynamic Changes in the Glucose Metabolism in Mouse Models of Lung Cancer

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Utilizing 18F-FDG PET/CT Imaging and Quantitative Histology to Measure Dynamic Changes in the Glucose Metabolism in Mouse Models of Lung Cancer
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Utilizing 18F-FDG PET/CT Imaging and Quantitative Histology to Measure Dynamic Changes in the Glucose Metabolism in Mouse Models of Lung Cancer

Published on: July 21, 2018

Area of Science:

  • Oncology
  • Molecular Imaging
  • Radiopharmaceuticals

Background:

  • Positron emission tomography (PET) with tumour-targeting radiopharmaceuticals is widely used in oncology.
  • PET/CT combines molecular and morphologic imaging for comprehensive staging.
  • 18-F-fluorodeoxyglucose (FDG) is the most common PET/CT radiopharmaceutical in clinical oncology.

Purpose of the Study:

  • To discuss the applications and indications of FDG PET/CT in oncology.
  • To review current literature on FDG PET/CT for diagnosis, staging, and recurrence detection.
  • To highlight the role of FDG PET/CT in assessing therapy response and influencing treatment decisions.

Main Methods:

  • Review of current literature on FDG PET/CT applications in oncology.
  • Focus on primary diagnosis, staging, and detection of recurrent disease.
  • Discussion of FDG PET/CT in assessing therapy response and treatment planning.

Main Results:

  • FDG PET/CT is established for diagnosis, staging, and restaging of various cancers.
  • The technique is particularly emphasized for lung cancer, lymphoma, head and neck cancer, melanoma, and breast cancer.
  • Growing evidence supports FDG PET/CT's value in evaluating therapy response and guiding treatment.

Conclusions:

  • FDG PET/CT is an efficient tool for comprehensive cancer staging and restaging.
  • Its role extends beyond diagnosis to include therapy response assessment, influencing clinical decision-making.
  • FDG PET/CT is a valuable modality for managing patients across various oncological entities.