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Updated: May 23, 2026

Atom Transfer Radical Polymerization of Functionalized Vinyl Monomers Using Perylene as a Visible Light Photocatalyst
Published on: April 22, 2016
Access to aliphatic ester derivatives via visible-light-induced radical alkoxycarbonylation of unactivated alkenes
Liulin Jiao1, Tongtong Zhao1, Liu Feng1
1Key Laboratory of Drug-Targeting and Drug Delivery System of the Education Ministry and Sichuan Province, Sichuan Engineering Laboratory for Plant-Sourced Drug, West China School of Pharmacy, Sichuan University, Chengdu 610041, China.
Abstract:
This study presents a robust novel strategy for the alkoxycarbonyl difunctionalization of unactivated alkenes. Using the alkoxycarbonyl radical donors we previously designed and synthesized, photoinduced efficient generation of alkoxycarbonyl radicals with varying carbon chain lengths enables addition to unactivated alkenes, which triggers intramolecular distal functional group migration, successfully affording aliphatic carboxylate derivatives. This protocol features a broad substrate scope and mild reaction conditions, and its potential synthetic utility was further evidenced by compatibility tests with natural product-derived molecules, scale-up reactions, and subsequent derivatizations.
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