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Empirical Comparison of Causal Machine Learning and Post-Hoc AI Interpretability Models for Risk Factor Analysis: An
David Vicente Alvarez1, Milena Abbiati1, Alban Bornet1
1University of Geneva, Switzerland.
Studies in Health Technology and Informatics
|May 23, 2026
Summary
Medical student specialty choice significantly impacts healthcare access. Strong motivations for surgery or general practice strongly influence career paths, while psychological traits show minimal impact.
Area of Science:
- Medical Education
- Health Services Research
- Computational Statistics
Background:
- Specialty choice among medical students is critical for equitable healthcare access.
- Previous research primarily described specialty choice patterns.
- Emerging predictive models can identify influential factors but may conflate association with causation.
Purpose of the Study:
- To investigate the causal relationship between medical student motivations and personality traits with their eventual specialty career choice.
- To compare causal inference methods with predictive model explanations (SHAP) for understanding specialty selection drivers.
Main Methods:
- Utilized Double/debiased machine learning (DoubleML) for causal effect estimation.
- Analyzed data from 399 medical students, assessing Year 4 motivations and Big Five personality traits.
- Correlated these factors with Year 6 specialty career choices (person-oriented vs. technically oriented).
Main Results:
- High motivation for surgery (level 6) decreased person-oriented choices by 0.37 (p < .001).
- High motivation for general practice increased person-oriented choices by 0.265 (p < .001).
- Psychological traits did not show significant effects (p > 0.05); SHAP explanations diverged from causal effects for weaker motivations and personality traits.
Conclusions:
- Specific motivations, particularly for surgery and general practice, are strong predictors of medical specialty choice.
- SHAP values from predictive models should be interpreted cautiously as they may not reflect true causal influence, especially for weaker or correlated factors.
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