Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Regulation of Stroke Volume

Regulation of Stroke Volume

The regulation of stroke volume, which is the amount of blood the heart pumps out during each heartbeat, is critical for maintaining a healthy circulatory system. Stroke volume is influenced by three main factors: preload, contractility, and afterload.
Preload refers to the degree of stretch on the heart before it contracts. It's analogous to the stretching of a rubber band; the more it's stretched, the more forcefully it snaps back. This concept is encapsulated in the Frank-Starling law of the...

Venous Thrombosis III: Interprofessional Care

Venous Thrombosis III: Interprofessional Care

Venous thrombosis requires effective prevention and treatment strategies to improve patient outcomes and reduce potential complications.Prevention StrategiesHealthcare providers must prioritize preventing venous thromboembolism (VTE) for all adult patients upon admission. Interventions depend on bleeding and thrombosis risk, medical history, current medications, diagnoses, planned procedures, and patient preferences. Patients on bed rest should change positions every two hours and, if not...

Ischemic Heart Disease: Overview

Ischemic Heart Disease: Overview

Ischemic heart disease occurs when the heart's blood supply dwindles, causing an ominous lack of oxygen and nutrients. This deficiency, stemming from reduced or obstructed blood flow, spells danger, leading to heart muscle damage and dysfunction.
Atherosclerosis, the primary malefactor, orchestrates this dangerous condition. It manifests as the accumulation of fatty deposits, akin to insidious plaques, within arterial walls. As time elapses, these plaques metamorphose, hardening and narrowing...

Coronary Artery Disease IV: Preventive Measures

Coronary Artery Disease IV: Preventive Measures

Effective preventive measures for coronary artery disease (CAD) focus on controlling modifiable risk factors, including cholesterol abnormalities and lifestyle changes.Cholesterol ManagementFirst, the Mediterranean diet and the American Heart Association advocate for maintaining low-density lipoprotein (LDL) cholesterol levels below 100 mg/dL, with a more stringent recommendation of below 70 mg/dL for individuals at high risk. LDL cholesterol, often termed "bad cholesterol," can lead to the...

Atherosclerosis III: Management

Atherosclerosis III: Management

Management of atherosclerosis involves an integrated strategy encompassing pharmacological treatment, surgical interventions, lifestyle changes, and nutrition therapy to address the multifactorial nature of the disease.Pharmacological TherapyA cornerstone of atherosclerosis management is the use of pharmacological agents. Statins, such as atorvastatin, are pivotal in inhibiting HMG-CoA reductase, an enzyme that catalyzes an initial step in cholesterol synthesis in the liver. This reduction in...

Ischemic Stroke ll: Pathophysiology

Ischemic Stroke ll: Pathophysiology

An ischemic stroke occurs when a cerebral blood vessel becomes obstructed, most often by a thrombus or embolus, interrupting the delivery of oxygen and glucose to brain tissue. Because neurons rely on continuous aerobic metabolism, energy failure begins within minutes of reduced perfusion. The region receiving the least blood flow becomes the infarct core, an area of irreversible cellular death. Surrounding this core lies the penumbra, a zone of hypoperfused but still viable tissue that is...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Real-World Practice in Secondary Stroke Prevention Following Embolic Stroke of Undetermined Source: Secondary Analysis of the CASPR Registry.

Neurology. Clinical practice·2026

Same author

Genetic Risk for Alzheimer Disease, Midlife Hypertension, and Dementia: The ARIC Neurocognitive Study.

Neurology·2026

Same author

Cognition After Stroke: It Is a Long Story.

Stroke·2026

Same author

Message From the Editors to Our Reviewers.

Neurology·2026

Same author

Maternal age and pregnancy-related cardiovascular complications.

Nature communications·2026

Same author

Prior Myocardial Infarction and Cognitive Decline: The REGARDS Cohort.

Stroke·2026

Search research articles

Related Experiment Video

Updated: May 26, 2026

Optimized Management of Endovascular Treatment for Acute Ischemic Stroke

Optimized Management of Endovascular Treatment for Acute Ischemic Stroke

Published on: January 18, 2018

Trends in Vascular Risk Factor Control Among US Adults With Prior Stroke: 1999 to 2023.

Wells Andres¹, Aaron Rothstein², Sabrina Abbruzzese²

¹Department of Neurology New York University Grossman School of Medicine New York NY USA.

Journal of the American Heart Association

|May 25, 2026

Summary

Fewer than 10% of US adults with stroke met all 4 key risk factor control guidelines. Improvements in managing glycemia, blood pressure, lipids, and smoking are needed to prevent recurrent strokes.

Keywords:

epidemiology guidelines stroke

Related Experiment Videos

Last Updated: May 26, 2026

Optimized Management of Endovascular Treatment for Acute Ischemic Stroke

Optimized Management of Endovascular Treatment for Acute Ischemic Stroke

Published on: January 18, 2018

Area of Science:

Cardiovascular Disease Epidemiology
Public Health Research
Stroke Prevention Strategies

Background:

Effective management of modifiable risk factors is crucial for preventing recurrent strokes.
This study examines trends in vascular risk factor control among US adults who have experienced a stroke.

Purpose of the Study:

To analyze trends in the control of key vascular risk factors (hyperglycemia, hyperlipidemia, hypertension, smoking) in US adults post-stroke.
To assess the proportion of stroke survivors meeting guideline-recommended targets for these risk factors over time.

Main Methods:

Analysis of National Health and Nutrition Examination Surveys data from 1999-2023 for participants with self-reported stroke.
Defined guideline targets for hemoglobin A1c, LDL cholesterol, blood pressure, and smoking status.
Calculated age-standardized means and prevalence of meeting targets across defined epochs.

Main Results:

Mean hemoglobin A1c increased, while LDL cholesterol decreased; blood pressure remained stable.
Glycemic control guideline adherence declined, but lipid control adherence improved.
Prevalence of meeting smoking and blood pressure guidelines was stable; fewer than 10% met all four targets.

Conclusions:

A small proportion of US adults with stroke achieve optimal control of all major vascular risk factors.
Current strategies for managing glycemia, blood pressure, lipids, and smoking cessation require enhancement to reduce recurrent stroke burden.