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Functional Rice Enriched With Resistant Starch Ameliorates Metabolic Dysregulation in High-Fat Diet-Induced Obese
Seung Tae Im1, Ho-Young Park2, Ha Ram Kim1
1Research Group of Food Processing, Korea Food Research Institute, Wanju, Republic of Korea.
Journal of Food Science
|May 26, 2026
Summary
Resistant starch-enriched rice effectively combats obesity and metabolic disorders. This functional carbohydrate improves glucose and lipid metabolism, offering a dietary strategy against high-fat diet-induced complications.
Area of Science:
- Nutrition Science
- Metabolic Health
- Food Science
Background:
- Resistant starch (RS) influences glucose and lipid metabolism.
- High-fat diets (HFD) induce metabolic disorders.
- Developing functional foods to manage metabolic health is crucial.
Purpose of the Study:
- To develop RS-enriched high-amylose rice (R-HAR) using citric acid treatment.
- To evaluate R-HAR's efficacy in ameliorating HFD-induced metabolic disorders in mice.
Main Methods:
- R-HAR was prepared via a mild citric acid-assisted thermal process.
- Mice were fed HFD supplemented with varying amounts of R-HAR.
- Metabolic parameters including body weight, adiposity, serum lipids, glucose, insulin, and liver histology were assessed.
Main Results:
- R-HAR supplementation significantly reduced body weight gain and adiposity.
- R-HAR improved lipid profiles (lowered cholesterol, LDL-C, ALT, AST) and increased adiponectin.
- R-HAR ameliorated insulin resistance (reduced glucose, insulin, HOMA-IR) and hepatic steatosis.
Conclusions:
- Citric acid-treated R-HAR effectively alleviates HFD-induced metabolic disorders.
- The enhanced RS content in R-HAR contributes to improved metabolic balance.
- R-HAR is a promising functional carbohydrate for preventing obesity-related metabolic complications.
