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Updated: May 28, 2026

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Combining Reflectance Confocal Microscopy with Optical Coherence Tomography for Noninvasive Diagnosis of Skin Cancers via Image Acquisition
Published on: August 18, 2022
Clinical and Dermoscopic Characterization of Mixed-Type Basal Cell Carcinoma
Fethi Zaid1, Kerem Balan1, Gonca Elçin1
1Department of Dermatology and Venereology, Hacettepe University Faculty of Medicine, Ankara, Turkey.
Dermatology Practical & Conceptual
|May 26, 2026
Summary
Dermoscopy can help identify mixed-type basal cell carcinoma (BCC) and its components, aiding in treatment decisions. Specific dermoscopic features correlate with different BCC subtypes and risk levels.
Area of Science:
- Dermatology
- Oncology
- Pathology
Background:
- Basal cell carcinoma (BCC) is a common skin cancer requiring accurate histopathological subtyping for effective management.
- While dermoscopic features of single BCC subtypes are known, those of mixed-type BCC remain less understood.
Purpose of the Study:
- To analyze demographic data of patients with single and mixed-type BCC.
- To investigate the correlation between clinical/dermoscopic findings and BCC histopathological subtypes.
Main Methods:
- Analysis of 186 BCC lesions from 157 patients.
- Correlation of dermoscopic features with histopathological subtypes, including single and mixed-type BCC.
Main Results:
- Mixed-type BCC was frequent (37.6%), with nodular-infiltrative and nodular-superficial being common combinations.
- Dermoscopic features like short fine telangiectasia and scales were more prevalent in mixed-type BCC.
- Specific dermoscopic patterns (e.g., wheel-like structures, dotted/glomerular vessels, arborizing vessels) correlated with BCC subtype components and high-risk features.
Conclusions:
- Dermoscopic findings are valuable for recognizing mixed-type BCC and its components.
- Dermoscopy can assist in differentiating BCC subtypes and guiding treatment strategies.

