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Related Concept Videos

Kidney Transplant I: Introduction01:28

Kidney Transplant I: Introduction

A kidney transplant is a surgical approach that involves replacing a non-functioning kidney with a healthy one from a donor. This procedure is often a treatment option for end-stage renal disease (ESRD) patients. The method requires careful recipient selection, including evaluating various medical and psychosocial factors. These criteria vary between transplant centers but generally include assessments of the patient's overall health, adherence to medical recommendations, and lifestyle...
Kidney Transplant II: Surgical Procedure01:26

Kidney Transplant II: Surgical Procedure

Preoperative ManagementThe primary goals of preoperative management in kidney transplantation are to optimize the patient’s metabolic state and prepare them for surgery through diet adjustments, necessary dialysis, and tailored medical treatment. This phase also involves comprehensive infection screening and patient education about the surgical procedure and postoperative care to improve outcomes and adherence.Medical ManagementA comprehensive evaluation is required for both the living donor...
Tissue Transplantation01:24

Tissue Transplantation

Tissue transplantation is a significant medical procedure involving the transfer of cells, tissues, or organs from a donor to a recipient, with the primary aim of restoring lost functions. This procedure is crucial in treating a broad spectrum of diseases, including kidney diseases, liver failure, heart disease, and certain types of cancers.
The Biology of Tissue Transplantation
The biology of tissue transplantation hinges on the Major Histocompatibility Complex (MHC) molecules. These molecules...
Bone Marrow Sampling and Transplants01:22

Bone Marrow Sampling and Transplants

Bone marrow transplant is a potential cure for several diseases, including cancer and specific genetic disorders. Notably, this procedure is applicable for patients suffering from aplastic anemia, certain types of leukemia, severe combined immunodeficiency disease (SCID), Hodgkin's disease, non-Hodgkin's lymphoma, multiple myeloma, thalassemia, sickle-cell disease, and certain cancers.
The transplant begins with high doses of chemotherapy and radiation treatment, which aim to destroy the...

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Second Report of the American Intestinal Transplant Working Group: New Insights Into Risk Factors, Treatment Regimens, and Outcomes of Malignancy After Intestinal Transplantation.

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Related Experiment Video

Updated: May 29, 2026

Small Bowel Transplantation In Mice
36:30

Small Bowel Transplantation In Mice

Published on: August 20, 2007

Rationale of Living Donor Small Bowel Transplantation.

Maria Jimena Alaniz1, Murad M Alqadi2, Pierpaolo Di Cocco1

  • 1Division of Transplantation, Department of Surgery, University of Illinois at Chicago, Chicago, IL, USA.

Gastroenterology Clinics of North America
|May 27, 2026
PubMed
Summary

Living donor intestinal transplantation offers a timely solution for patients with intestinal failure. This approach provides planned surgical advantages, especially crucial for pediatric recipients requiring precise size matching.

Keywords:
International intestinal transplant registryIntestinal failureIntestinal transplantationLiving donor intestinal transplantation

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Related Experiment Videos

Last Updated: May 29, 2026

Small Bowel Transplantation In Mice
36:30

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Published on: August 20, 2007

Orthotopic Small Bowel Transplantation in Rats
09:16

Orthotopic Small Bowel Transplantation in Rats

Published on: November 6, 2012

A Rat Graft Rejection Model of Intestinal Transplantation with Exteriorized Ileostomy for Longitudinal Prognosis Assessment
08:25

A Rat Graft Rejection Model of Intestinal Transplantation with Exteriorized Ileostomy for Longitudinal Prognosis Assessment

Published on: June 10, 2025

Area of Science:

  • Transplantation Surgery
  • Gastroenterology
  • Pediatric Surgery

Background:

  • Intestinal failure necessitates complex management, often including transplantation.
  • Deceased donor organ availability can be a limiting factor for timely intervention.
  • Living donor intestinal transplantation presents an alternative to deceased donor grafts.

Purpose of the Study:

  • To elucidate the rationale and benefits of living donor intestinal transplantation.
  • To highlight the advantages of elective surgery and planned graft procurement.
  • To emphasize the critical role of size matching in pediatric intestinal transplantation.

Main Methods:

  • Graft procurement from a healthy living donor (often a family member).
  • Implantation of a segmental small-intestine graft into the recipient.
  • Surgical planning focused on predictable timing and short ischemia.

Main Results:

  • Provides a timely alternative when deceased donor waiting times are prohibitive.
  • Facilitates elective surgery with controlled timing and reduced ischemia.
  • Offers potential immunologic compatibility advantages and critical size matching for pediatric cases.

Conclusions:

  • Living donor intestinal transplantation is a viable option for intestinal failure.
  • Planned surgery offers significant practical and immunological benefits.
  • This approach is particularly advantageous for pediatric recipients requiring precise size matching.