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[Multidimensional clinical phenotypes of obstructive sleep apnea hypopnea syndrome based on unsupervised clustering

Zihan Xia1, Xiaoxin Niu1, Yuqi Yuan1

  • 1Department of Otorhinolaryngology Head and Neck Surgery，the Second Affiliated Hospital of Xi'an Jiaotong University，Xi'an，710004，China.

Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi = Journal of Clinical Otorhinolaryngology Head and Neck Surgery
|May 28, 2026
PubMed
Summary

Obstructive sleep apnea-hypopnea syndrome (OSAHS) patients can be classified into four distinct phenotypes based on sleep and symptom data. This multidimensional approach aids in developing personalized treatment strategies for OSAHS.

Keywords:
cluster analysisobstructive sleep apnea hypopnea syndromepolysomnographyprecision medicinevisual analysis

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Sleep apnea is a condition where breathing stops intermittently during sleep, often leading to significant health issues. Each episode can last from 10 to 20 seconds or more and is frequently accompanied by a brief arousal from sleep. This disturbance, largely unnoticed by the individual, can lead to severe daytime fatigue. Commonly, individuals seek help after being informed by their partners about loud snoring and noticeable breathing pauses during sleep.
The condition is more prevalent among...