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A New Technique for Treating Low-risk Prostate Cancer—Super Active Surveillance
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Published on: November 7, 2025

[Screening for prostate cancer; a screening program is favored over current opportunistic testing].

Roderick C N van den Bergh1,2, Monique J Roobol1, Pim J van Leeuwen3

  • 1Erasmus MC, afd. Urologie, Rotterdam.

Nederlands Tijdschrift Voor Geneeskunde
|June 2, 2026
PubMed
Summary

The Netherlands lacks a national prostate cancer screening program, leading to overdiagnosis and inequality. A modern, risk-based approach could reduce mortality while minimizing unnecessary testing, necessitating a pilot study.

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Published on: November 2, 2013

Area of Science:

  • Oncology
  • Public Health
  • Health Policy

Background:

  • No national prostate cancer (PCa) screening program exists in The Netherlands.
  • Current individual early detection via PSA testing is common but inefficient, leading to overdiagnosis and social inequality.
  • Concerns about overdiagnosis have historically prevented population-based screening initiatives.

Purpose of the Study:

  • To propose a modern, risk-based, imaging-guided screening approach for prostate cancer (PCa).
  • To reduce PCa-related mortality and metastasis while enhancing quality of life for those benefiting from early detection.
  • To minimize unnecessary testing and overdiagnosis in men unlikely to benefit from screening.

Main Methods:

  • The study proposes a conceptual framework for a new screening strategy.
  • It emphasizes the need for a pilot implementation study to gather feasibility and sustainability data.
  • The approach integrates risk stratification and imaging guidance.

Main Results:

  • Current screening practices in The Netherlands are inefficient, contributing to overdiagnosis and health inequalities.
  • A risk-based, imaging-guided approach is suggested to improve outcomes and reduce harms.
  • A pilot study is deemed essential to validate the proposed screening model.

Conclusions:

  • A structured, risk-based, and imaging-guided prostate cancer screening program is needed in The Netherlands.
  • Such a program aims to balance early detection benefits with the risks of overdiagnosis and inefficiency.
  • Implementation of a pilot study is crucial for evaluating the feasibility and sustainability of a national screening program.