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Related Concept Videos

Glaucoma: Overview01:25

Glaucoma: Overview

Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
Open Angle Glaucoma: Treatment01:27

Open Angle Glaucoma: Treatment

In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
Angle Closure Glaucoma: Treatment01:28

Angle Closure Glaucoma: Treatment

Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
Cancer Therapies02:49

Cancer Therapies

Cancer therapies are various modes of treatment, such as surgery, radiation therapy, and chemotherapy that are administered to cancer patients.
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
Cancer02:18

Cancer

Cancers arise due to mutations in genes involved in the regulation of cell division, which leads to unrestricted cell proliferation. Modern science and medicine have made great strides in the understanding and treatment of cancer, including eradicating cancer in some patients. However, there is still no cure for cancer. This is largely due to the fact that cancer is a large group of many diseases.
Photoreceptors and Visual Pathways01:22

Photoreceptors and Visual Pathways

At the molecular level, visual signals trigger transformations in photopigment molecules, resulting in changes in the photoreceptor cell's membrane potential. The photon's energy level is denoted by its wavelength, with each specific wavelength of visible light associated with a distinct color. The spectral range of visible light, classified as electromagnetic radiation, spans from 380 to 720 nm. Electromagnetic radiation wavelengths exceeding 720 nm fall under the infrared category, whereas...

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Related Experiment Video

Updated: Jun 3, 2026

Glaucoma-inducing Procedure in an In Vivo Rat Model and Whole-mount Retina Preparation
08:30

Glaucoma-inducing Procedure in an In Vivo Rat Model and Whole-mount Retina Preparation

Published on: March 12, 2016

Cancer and glaucoma: A systematic review.

Tammy Si Yue Yim1, Titus Hutch Jr Yi Zheng Yim2, Kevin Kun Peng Wang3

  • 1Department of General Medicine, Tan Tock Seng Hospital, Singapore, Singapore.

European Journal of Ophthalmology
|June 2, 2026
PubMed
Summary
This summary is machine-generated.

This review highlights the link between cancer and glaucoma, finding increased glaucoma risk in cancer patients. Glaucoma may signal complications in intraocular cancers, necessitating monitoring and management strategies.

Keywords:
Glaucomacancerintraocular pressurereview

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Laser Capture Microdissection of Highly Pure Trabecular Meshwork from Mouse Eyes for Gene Expression Analysis
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Laser Capture Microdissection of Highly Pure Trabecular Meshwork from Mouse Eyes for Gene Expression Analysis

Published on: June 3, 2018

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Last Updated: Jun 3, 2026

Glaucoma-inducing Procedure in an In Vivo Rat Model and Whole-mount Retina Preparation
08:30

Glaucoma-inducing Procedure in an In Vivo Rat Model and Whole-mount Retina Preparation

Published on: March 12, 2016

Laser Capture Microdissection of Highly Pure Trabecular Meshwork from Mouse Eyes for Gene Expression Analysis
13:47

Laser Capture Microdissection of Highly Pure Trabecular Meshwork from Mouse Eyes for Gene Expression Analysis

Published on: June 3, 2018

Area of Science:

  • Ophthalmology
  • Oncology
  • Systematic Review

Background:

  • Glaucoma and cancer are prevalent, debilitating diseases with significant morbidity.
  • Existing literature lacks a systematic review of the complex interactions between cancer and glaucoma.
  • Understanding these relationships is crucial for patient care and prognosis.

Purpose of the Study:

  • To systematically review the association between intraocular/non-ocular cancers and glaucoma prevalence/etiology.
  • To explore glaucoma's role as a risk factor for intraocular cancer complications.
  • To examine glaucoma management in cancer patients, especially secondary to cancer therapies.

Main Methods:

  • Systematic literature search across three databases up to July 2025.
  • Search terms included variants of 'cancer' and 'glaucoma'.
  • Narrative synthesis of findings from included studies.

Main Results:

  • 18 studies reported increased glaucoma prevalence in cancer patients (intraocular and non-ocular).
  • 15 studies indicated higher risk of invasion, metastasis, and poor prognosis in intraocular cancers co-occurring with glaucoma.
  • Cancer therapies like corticosteroids can elevate intraocular pressure (IOP), while androgen deprivation therapy may lower glaucoma risk.

Conclusions:

  • The established link between glaucoma and cancer warrants consideration of glaucoma monitoring and management strategies post-cancer diagnosis or therapy.
  • Glaucoma may serve as an early indicator of complications in intraocular cancers.
  • Further research into managing cancer-related glaucoma is essential.