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Updated: Jun 4, 2026
15:29
Microscopy-based Assays for High-throughput Screening of Host Factors Involved in Brucella Infection of Hela Cells
Published on: August 5, 2016
Brucellosis Surveillance - United States, 2010-2024.
Morbidity and Mortality Weekly Report. Surveillance Summaries (Washington, D.C. : 2002)
|June 2, 2026
Summary
Brucellosis cases in the U.S. were analyzed using the 2010 CSTE definition. Key exposures include consuming unpasteurized products and animal contact, especially with wild game.
Area of Science:
- Zoonotic disease epidemiology
- Infectious disease surveillance
Background:
- Brucellosis is a zoonotic disease caused by Brucella bacteria, transmissible to humans from infected animals or their products.
- This report details U.S. brucellosis cases following the 2010 Council of State and Territorial Epidemiologists (CSTE) case definition adoption.
Purpose of the Study:
- To analyze U.S. brucellosis cases reported between 2010 and 2024.
- To identify key exposure routes and risk factors associated with human brucellosis infections.
Main Methods:
- Analysis of data from the National Notifiable Diseases Surveillance System (NNDSS) and supplemental case report forms (CRFs).
- Application of the 2010 CSTE brucellosis case definition to determine case status.
- Review of clinical specimen testing data from the CDC.
Main Results:
- A total of 1,796 confirmed and probable brucellosis cases were reported from 2010-2024.
- Among cases meeting the CSTE definition, 61% reported travel, with 80% of those traveling internationally reporting consumption of unpasteurized dairy or undercooked meat (73%).
- Non-travel-related exposures included animal contact (62%), particularly skinning/slaughtering (41%) and hunting (40%) wild animals.
Conclusions:
- Inadequate clinical or laboratory data excluded nearly half of CRFs from analysis.
- Identified exposures include unpasteurized dairy/undercooked meat (especially from abroad or wild game) and animal contact (particularly wild game handling).
- Public health messaging should focus on reducing exposure risks from these sources and promoting safe practices for hunters.
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