Enhancing the assessment of deglutition function in preterm infants with mechano-acoustic analysis and machine

Emily Bordier1, Eric B Ortigoza2

  • 1Applied Clinical Research, School of Health Professions, UT Southwestern Medical Center.

Insights

Mechano-acoustic analysis shows promise for assessing swallowing in preterm infants. Further research is needed to develop machine learning tools for accurate diagnosis of deglutition dysfunction.

Area of Science:

  • Neonatal physiology
  • Swallowing biomechanics
  • Computational diagnostics

Background:

  • Clinical indicators for deglutition dysfunction in preterm infants are not well-defined.
  • Mechano-acoustic analysis (e.g., cervical auscultation, accelerometry) shows potential for classifying swallow physiology.
  • Machine learning (ML) enhances diagnostic performance for complex deglutition data in various populations.

Purpose of the Study:

  • To investigate the feasibility and usability of mechano-acoustic analysis combined with ML for identifying indicators of deglutition impairment in preterm infants.
  • To improve diagnostic accuracy and clinical prediction of clinical swallow evaluations (CSEs) in this population.

Main Methods:

  • A narrative review of studies was conducted using PubMed and Ovid databases.
  • No filters were applied to the publication year.

Main Results:

  • Twelve relevant records were identified.
  • Preliminary studies indicate significant findings in maturational changes of mechano-acoustic deglutition features.
  • Research on ML for mechano-acoustic analysis in preterm infants is currently lacking, with no published studies on deglutition dysfunction indicators or normative data for healthy neonates.

Conclusions:

  • Mechano-acoustic analysis is a feasible technique for evaluating deglutition in preterm infants.
  • Future longitudinal studies need to establish normative values, correlate signals with kinematics, and standardize features to enhance clinical utility.
  • Further research is required to assess the diagnostic performance of ML algorithms for improved classification and prediction of deglutition function in preterm infants.
Abstract