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Establishment of Rat Models Mimicking Gender-affirming Hormone Therapies
Published on: January 10, 2025
Obstetric Care of Transgender and Gender-Diverse People
1Department of Obstetrics, Gynecology, and Reproductive Sciences, University of California San Diego Health, 9300 Campus Point Drive, Mail Code 7433, San Diego, CA 92037-7433, USA.
Abstract:
Best practice guidelines for preconception, pregnancy, and postpartum care of transgender men do not exist due to a lack of large-scale data. Decisions about testosterone use in the preconception and postpartum period should be weighed against risks to the pregnancy and exacerbation of gender dysphoria. Because patients' experiences with bodily changes during and after pregnancy can vary from gender-affirming to dysphoric, prenatal and peripartum care should aim to be individualized through a gender-affirming lens. Obstetric outcomes do not seem to be worse in transgender men, but more robust studies are needed for generalizability.
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