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A Direct, Regioselective and Atom-Economical Synthesis of 3-Aroyl-N-hydroxy-5-nitroindoles by Cycloaddition of 4-Nitronitrosobenzene with Alkynones
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A Direct, Regioselective and Atom-Economical Synthesis of 3-Aroyl-N-hydroxy-5-nitroindoles by Cycloaddition of 4-Nitronitrosobenzene with Alkynones

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Larock Indolization of Chloroanilines for the Synthesis of Noncanonical Tryptophans and Macrocyclic Compounds

Oniya L Valencia1, Viet D Nguyen1

  • 1Process Research & Development, Merck & Co., Inc., MRL, Rahway, New Jersey 07065, United States.

The Journal of Organic Chemistry
|June 5, 2026
PubMed

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