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Localized Infrared Hyperthermia as an Adjunctive Therapy for Long-Standing Hailey-Hailey Disease: A Case Report.
Hongye Wu1, Yonghong Lu1, Yanyan Feng1
1West China School of Medicine, Sichuan University, Sichuan University Affiliated Chengdu Second People's Hospital, Chengdu Second People's Hospital, Chengdu, People's Republic of China.
Clinical, Cosmetic and Investigational Dermatology
|June 9, 2026
Summary
Localized infrared hyperthermia offers a safe, non-invasive adjunctive treatment for recalcitrant Hailey-Hailey disease (HHD). This therapy provided sustained disease control and improved quality of life in a long-standing HHD case.
Area of Science:
- Dermatology
- Medical Technology
- Genodermatoses
Background:
- Hailey-Hailey disease (HHD) is a rare, chronic genodermatosis causing painful erosions.
- Management is challenging for patients with long-standing, relapsing HHD unresponsive to conventional therapies.
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Increased Body Temperature
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Methods of reducing fever
The signs and symptoms of fever include hot and dry skin, flushed face, thirst, muscle aches, anorexia, headache, tachycardia, tachypnea, and fatigue. Elevated body temperature is reduced using two methods: pharmacological and nonpharmacological. Proper identification and treatment of the root cause of a fever is of utmost importance.
Pharmacological Methods of Reducing Fever:
Pharmacological Methods of Reducing Fever:

