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Updated: Jun 10, 2026

Utilizing Percutaneous Ventricular Assist Devices in Acute Myocardial Infarction Complicated by Cardiogenic Shock
06:10

Utilizing Percutaneous Ventricular Assist Devices in Acute Myocardial Infarction Complicated by Cardiogenic Shock

Published on: June 12, 2021

Acute Myocardial Infarction versus Acute Decompensated Heart Failure in Cardiogenic Shock: A Systematic Review and

Mehmet Birhan Yilmaz1, Mustafa Eray Kilic1, Jan Biegus2

  • 1Dokuz Eylul University, Faculty of Medicine, Department of Cardiology, Izmir, Türkiye.

European Journal of Heart Failure
|June 9, 2026
PubMed

Insights

Acute myocardial infarction (AMI-CS) cardiogenic shock presents more severely than acutely decompensated heart failure (ADHF-CS) cardiogenic shock, with increased need for mechanical support and higher short-term mortality.

Area of Science:

  • Cardiology
  • Critical Care Medicine
  • Health Services Research

Background:

  • Cardiogenic shock (CS) has distinct phenotypes: acute myocardial infarction (AMI-CS) and acutely decompensated heart failure (ADHF-CS).
  • Comparative evidence between these CS phenotypes is limited.
  • This meta-analysis aimed to compare presentation, management, and outcomes of AMI-CS versus ADHF-CS.

Purpose of the Study:

  • To compare the clinical presentation of AMI-CS and ADHF-CS.
  • To compare the management strategies employed for AMI-CS and ADHF-CS.
  • To compare the short-term mortality rates between AMI-CS and ADHF-CS.

Main Methods:

  • A meta-analysis of observational studies published between 2019 and 2025.
  • Studies compared patients with AMI-CS and ADHF-CS.
  • Random-effects models were used to estimate odds ratios and mean differences for primary outcome (short-term mortality) and secondary outcomes.

Main Results:

  • AMI-CS patients were older with higher ejection fraction but presented with more severe shock (cardiac arrest, SCAI stage D/E).
  • Temporary mechanical circulatory support was used more frequently in AMI-CS.
  • Short-term mortality was significantly higher in the AMI-CS group (OR 1.58).

Conclusions:

  • AMI-CS exhibits a more fulminant presentation, greater need for mechanical support, and higher short-term mortality compared to ADHF-CS.
  • A dual-axis framework integrating shock severity and etiology is proposed for future research.
  • Prospective studies with detailed phenotyping are needed for validation.
Abstract

Keywords:
acute myocardial infarctioncardiogenic shockheart failuremechanical circulatory supportmeta-analysismortality

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