Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Imaging Studies for Cardiovascular System I:Echocardiography01:17

Imaging Studies for Cardiovascular System I:Echocardiography

Cardiac imaging studies encompass a wide range of noninvasive and minimally invasive techniques designed to visualize the heart's structure and function in detail. One such technique is echocardiography, which uses high-frequency ultrasound waves to produce detailed images of the heart, known as echocardiograms.
Indications: Echocardiography is utilized to diagnose heart failure, valve disorders, and myocardial infarction. It also assesses cardiac structures' size, shape, and motion, evaluates...
Imaging Studies for Cardiovascular System II:Types of Echocardiography01:20

Imaging Studies for Cardiovascular System II:Types of Echocardiography

Echocardiography plays a role in assessing cardiac health and detecting heart conditions, with various types providing critical insights for diagnosis and treatment.
Types of Echocardiography
Transthoracic Echocardiography (TTE)
TTE is the most common type of echocardiogram which involves placing a transducer on the patient's chest, emitting sound waves to create heart images. TTE is invaluable for evaluating the heart's size, structure, and motion, making it particularly useful for diagnosing...
Cardiomyopathy III: Hypertrophic Cardiomyopathy01:29

Cardiomyopathy III: Hypertrophic Cardiomyopathy

Hypertrophic cardiomyopathy, or HCM, is an autosomal dominant genetic disorder characterized by asymmetric left ventricular hypertrophy without ventricular dilation. It is more common in men and is typically diagnosed in young, athletic adults.EtiologyHCM is primarily genetic and is caused by mutations in genes encoding sarcomeric proteins. Researchers have identified over 1400 mutations across at least 11 different genes. Among these, the most frequently occurring mutations are found in the...
Cardiomyopathy I: Introduction and Classification01:25

Cardiomyopathy I: Introduction and Classification

Cardiomyopathy, or CMP, is a group of diseases affecting the myocardial structure, impairing its ability to pump blood effectively. This condition can lead to arrhythmias, heart failure, or sudden cardiac death.Cardiomyopathies are classified into primary and secondary categories:Primary Cardiomyopathy refers to conditions involving only the heart muscle that are often idiopathic (of unknown cause) or genetic. They primarily affect the myocardium without the involvement of other systemic...
Acute Coronary Syndrome III: Diagnostic Studies01:30

Acute Coronary Syndrome III: Diagnostic Studies

Diagnosing acute coronary syndrome or ACS begins with a thorough patient history. Notable symptoms include central, crushing chest pain radiating to the left arm, neck, jaw, or back, along with shortness of breath, sweating (diaphoresis), nausea, vomiting, dizziness, and palpitations.It is crucial to note any history of cardiac illnesses and assess risk factors, including age, gender, smoking, hypertension, diabetes, hyperlipidemia, and a sedentary lifestyle.During physical examination, vital...
Imaging Studies for Cardiovascular System VI: Calcium -Scoring CT01:25

Imaging Studies for Cardiovascular System VI: Calcium -Scoring CT

Calcium-Scoring CT ScanA calcium-scoring CT scan, also known as coronary artery calcium (CAC) scan, detects calcium deposits in the coronary arteries. This test assesses the risk of coronary artery disease (CAD), which can lead to cardiovascular events such as angina, heart failure, and sudden cardiac arrest.A calcium-scoring CT scan is generally recommended for individuals at intermediate risk of CAD without symptoms. It includes:Men aged 40-75 and women aged 50-75: Especially those with a...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Peripheral blood immune profiling reveals key signatures in newly diagnosed NK/T cell lymphoma patients.

Theranostics·2026
Same author

H3K18la-PSMG1 Axis in Bladder Cancer Progression: Curcumin as a Therapeutic Candidate.

International journal of biological sciences·2026
Same author

Lactate-driven H3K18 lactylation promotes cisplatin resistance in bladder cancer via HNRNPF-Parkin mediated mitophagy.

Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy·2026
Same author

Liposomal mitoxantrone plus tislelizumab in patients with relapsed or refractory extranodal natural killer/T-cell lymphoma: a phase 1b/2 trial.

Nature communications·2026
Same author

Experimental investigation of maximum-confidence measurements and their contextual advantages.

Optics express·2026
Same author

Towards a universal JPEG lossless recompression foundation model for pathology images: A transformer context modeling approach.

Medical image analysis·2026
Same journal

Evidence-Based Clinical Recommendations for the Appropriate Use of Diagnostic Tests in Pediatric Allergology: Focus on Asthma, Rhinoconjunctivitis, and Keratoconjunctivitis Vernal.

Journal of clinical medicine·2026
Same journal

Surgical and Transcatheter Approach of a Failed Mitral Valve Repair: A Comprehensive Review on Selecting the Most Suitable Approach.

Journal of clinical medicine·2026
Same journal

Hybrid Metaheuristic Feature Selection for Breast Cancer Detection in Digital Mammography: A Feasibility Study with Nested Validation, Benchmarking, and External Stress Testing.

Journal of clinical medicine·2026
Same journal

Identity Transformation and the Role of Accountability in Recovery from Problematic Pornography Use: A Phenomenological-Hermeneutical Study.

Journal of clinical medicine·2026
Same journal

Does Early Surgical Treatment in Degenerative Cervical Myelopathy Have a Favorable Clinical Outcome and Impact on Quality of Life?

Journal of clinical medicine·2026
Same journal

Shear Wave Elastography in Musculoskeletal Imaging: A Narrative Review.

Journal of clinical medicine·2026
See all related articles

Related Experiment Video

Updated: Jun 13, 2026

Ultrasonic Assessment of Myocardial Microstructure
10:53

Ultrasonic Assessment of Myocardial Microstructure

Published on: January 14, 2014

Multidimensional Structural Echocardiographic Patterns and Risk Score for Prognostic Stratification in Ischemic

Ruixuan Tang1,2, Yan Xu1, Xiao Zong1,2

  • 1Departments of Cardiology, Rui Jin Hospital, Shanghai Jiaotong University School of Medicine, 197 Rui Jin Road II, Shanghai 200025, China.

Journal of Clinical Medicine
|June 12, 2026
PubMed
Summary
This summary is machine-generated.

Multidimensional echocardiography reveals distinct structural patterns in ischemic cardiomyopathy (ICM). A novel structural risk score improves cardiovascular mortality prediction before revascularization, offering better risk stratification for patients with ICM.

Keywords:
echocardiographyischemic cardiomyopathypre-revascularization assessmentstructural remodelingventricular dilation

More Related Videos

High-frequency High-resolution Echocardiography: First Evidence on Non-invasive Repeated Measure of Myocardial Strain, Contractility, and Mitral Regurgitation in the Ischemia-reperfused Murine Heart
11:50

High-frequency High-resolution Echocardiography: First Evidence on Non-invasive Repeated Measure of Myocardial Strain, Contractility, and Mitral Regurgitation in the Ischemia-reperfused Murine Heart

Published on: July 9, 2010

Related Experiment Videos

Last Updated: Jun 13, 2026

Ultrasonic Assessment of Myocardial Microstructure
10:53

Ultrasonic Assessment of Myocardial Microstructure

Published on: January 14, 2014

High-frequency High-resolution Echocardiography: First Evidence on Non-invasive Repeated Measure of Myocardial Strain, Contractility, and Mitral Regurgitation in the Ischemia-reperfused Murine Heart
11:50

High-frequency High-resolution Echocardiography: First Evidence on Non-invasive Repeated Measure of Myocardial Strain, Contractility, and Mitral Regurgitation in the Ischemia-reperfused Murine Heart

Published on: July 9, 2010

Area of Science:

  • Cardiology
  • Echocardiography
  • Medical Imaging

Background:

  • Ischemic cardiomyopathy (ICM) involves complex structural remodeling not fully assessed by standard systolic metrics.
  • The utility of multidimensional echocardiographic data for pre-revascularization risk stratification in ICM is not well-defined.
  • Conventional echocardiography may underestimate the prognostic implications of structural changes in ICM.

Purpose of the Study:

  • To investigate if multidimensional structural echocardiographic data can enhance risk stratification in patients with ICM before revascularization.
  • To identify distinct structural remodeling patterns using unsupervised clustering.
  • To develop and validate a structural risk score derived from principal component analysis (PCA).

Main Methods:

  • Retrospective analysis of 989 ICM patients (derivation) and 482 (validation) undergoing coronary angiography and revascularization.
  • Analysis of eight pre-revascularization echocardiographic structural variables.
  • Unsupervised clustering for pattern identification and PCA for risk score derivation; Cox proportional hazards models for mortality association.

Main Results:

  • Three distinct structural clusters with varying chamber size, function, pulmonary pressures, and mitral regurgitation were identified.
  • The PCA-derived structural risk score independently predicted cardiovascular mortality in both derivation and validation cohorts.
  • Structural clusters and the risk score demonstrated superior discriminative performance compared to individual echocardiographic parameters.

Conclusions:

  • Multidimensional echocardiography reveals meaningful structural remodeling patterns in ICM.
  • A PCA-derived structural risk score provides robust prognostic information beyond traditional measures.
  • These approaches enable more precise pre-revascularization risk stratification for patients with ICM.