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Updated: Jun 13, 2026
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In Vivo Morphometric Analysis of Human Cranial Nerves Using Magnetic Resonance Imaging in Menière's Disease Ears and Normal Hearing Ears
Published on: February 21, 2018
Sexual Dimorphism and Population Variation in Median Nerve Morphometry: A Multi-Institutional Cadaveric Analysis.
Jessica Nguyen1, Alfredo A Torres-Rodriguez1, Mario Loomis2
1College of Osteopathic Medicine, Sam Houston State University, Conroe, TX 77304, USA.
Diagnostics (Basel, Switzerland)
|June 12, 2026
Summary
Median nerve anatomy varies by sex and population. This study provides crucial morphometric data for the Puerto Rican cohort, aiding surgical and imaging interpretations.
Area of Science:
- Anatomy
- Morphometry
- Neuroscience
Background:
- Median nerve anatomical variability has clinical significance.
- Quantitative morphometric data, especially by sex and population, is limited.
- Hispanic cadaveric cohorts are underrepresented in existing studies.
Purpose of the Study:
- To quantitatively analyze median nerve formation and morphometry.
- To investigate differences based on biological sex and population classification.
- To provide population-sensitive anatomical data for clinical applications.
Main Methods:
- Multi-institutional cadaveric study of 82 donors (164 limbs).
- Dissections from brachial plexus to distal forearm.
- Digital caliper measurements between standardized anatomical landmarks.
Main Results:
- Male specimens showed sex-specific proximal median nerve formation differences.
- The Puerto Rican cohort exhibited greater morphometric distances than Caucasian and African American cohorts.
- Normalized ratios suggest limb-size scaling influences absolute differences.
Conclusions:
- Provides standardized, landmark-based morphometric data for median nerve anatomy.
- Highlights the importance of population-specific data for surgical planning.
- Supports enhanced accuracy in imaging-based interpretations of median nerve morphology.
