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Functional Chitosan-Interpenetrating Networks: Next Generation Super-Adsorbents for Biomedical Applications
Khushi Verma1, Lalita Chopra1, Carlo Santulli2
1Department of Chemistry, University Institute of Sciences (UIS), Chandigarh University, Gharuan, Punjab 140413, India.
Polymers
|June 12, 2026
Summary
Chitosan-based interpenetrating networks (IPNs) enhance adsorption and stability for biomedical uses. These advanced materials offer tunable properties for applications like drug delivery and tissue engineering.
Area of Science:
- Biomaterials Science
- Polymer Chemistry
- Nanotechnology
Background:
- Chitosan offers biocompatibility but has limitations in adsorption efficiency and stability.
- Interpenetrating networks (IPNs) improve chitosan's properties by combining it with other polymers.
- Chitosan-based IPNs provide enhanced structural stability and a high density of adsorption sites.
Purpose of the Study:
- To review recent advancements in chitosan-based IPNs for super-adsorbent applications.
- To assess the fabrication, functionalization, and structure-property relationships of these materials.
- To highlight their biomedical applications and future potential.
Main Methods:
- Fabrication of chitosan-based interpenetrating polymer networks.
- Functionalization strategies to tailor adsorption properties.
- Characterization of network structure, porosity, swelling, and adsorption kinetics.
Main Results:
- Chitosan-based IPNs exhibit synergistic enhancements in physicochemical and adsorption properties.
- Tunable control over network structure, porosity, and swelling behavior is achieved.
- IPNs demonstrate effective adsorption and controlled release of therapeutic agents.
Conclusions:
- Chitosan-based IPNs are promising super-adsorbent materials for advanced biomedical applications.
- Their tunable nature allows for tailored adsorption properties for specific uses.
- Further research is needed to address scalability, stability, and clinical translation challenges.
