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Case Report: Large Cell Neuroendocrine Carcinoma of the Palatine Tonsil in a 76-Year-Old Patient
Agnieszka Bugaj1, Natalia Zagozda1, Piotr Nogal1
1Department of Otolaryngology, Head and Neck Surgery, Poznan University of Medical Sciences, Poznań, Poland.
Background:
Large cell neuroendocrine carcinoma (LCNEC) of the palatine tonsil is an extremely rare malignancy characterized by an aggressive clinical course and poor prognosis. Its nonspecific presentation often delays diagnosis.
Methods:
We present the case of a 76-year-old female patient admitted to the Emergency Department with throat bleeding as her sole symptom. A computed tomography (CT) scan revealed an infiltrate in the right palatine tonsil.
Results:
Following a tonsillectomy, histopathological examination confirmed LCNEC. PET-CT showed no distant metastases or local recurrence, and multidisciplinary consultation excluded adjuvant therapy due to age and comorbidities, opting for ongoing outpatient surveillance.
Conclusions:
This case highlights the importance of oncological vigilance in the differential diagnosis of nonspecific symptoms.
