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Updated: Jun 17, 2026
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Surgical Treatment for Benign Prostatic Hyperplasia: Holmium Laser Enucleation of the Prostate (HoLEP).
Published on: March 6, 2018
Holmium Laser Enucleation of the Prostate Versus Robot-Assisted Simple Prostatectomy for Benign Prostatic
Giulia Luiza Garcia1, Bernardo Fontel Pompeu1,2, Gabriel Leal Barone1
1University of São Caetano do Sul, São Paulo, Brazil.
Summary
Holmium laser enucleation of the prostate (HoLEP) offers better safety during surgery for benign prostatic obstruction (BPO) than robot-assisted simple prostatectomy (RASP). Functional outcomes are similar, but more research is needed for long-term effectiveness.
Area of Science:
- Urology
- Surgical Innovation
- Comparative Effectiveness
Background:
- Benign prostatic obstruction (BPO) management.
- Holmium laser enucleation of the prostate (HoLEP) as a BPO treatment.
- Debate on HoLEP vs. robot-assisted simple prostatectomy (RASP) efficacy.
Purpose of the Study:
- Compare HoLEP and RASP for BPO.
- Evaluate perioperative and functional outcomes.
- Provide updated evidence for clinical decision-making.
Main Methods:
- Systematic review and meta-analysis.
- Searched PubMed, Scopus, and Cochrane databases.
- Analyzed 13 studies with 1993 patients.
Main Results:
- HoLEP showed shorter operative time, lower transfusion rates, and fewer severe complications.
- Earlier catheter removal observed with HoLEP.
- Similar functional outcomes (IPSS, Qmax, QoL, sexual function) between HoLEP and RASP.
Conclusions:
- HoLEP demonstrates superior perioperative safety compared to RASP.
- Functional outcomes are largely comparable between the two procedures.
- High-quality studies are needed to confirm long-term HoLEP effectiveness.
