Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: Jun 18, 2026

Fat-Water Phantoms for Magnetic Resonance Imaging Validation: A Flexible and Scalable Protocol
07:59

Fat-Water Phantoms for Magnetic Resonance Imaging Validation: A Flexible and Scalable Protocol

Published on: September 7, 2018

Free-Breathing Fat Quantification Using a Phase Error-Corrected Cartesian Acquisition With Spiral Profile Ordering.

Philipp Braun1, Jonathan Stelter1, Stefan Ruschke1

  • 1Institute for Diagnostic and Interventional Radiology, School of Medicine and Health, TUM University Hospital, Technical University of Munich (TUM), Munich, Germany.

Magnetic Resonance in Medicine
|June 17, 2026
PubMed
Summary

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Multiparametric Free-Breathing 3D Whole-Heart Cardiac MR for Anatomical Bright- and Black-Blood Imaging With Co-Registered <math><semantics><mrow><msub><mrow><mi>T</mi></mrow> <mrow><mn>1</mn></mrow></msub> <mo>/</mo> <msub><mrow><mi>T</mi></mrow> <mrow><mn>2</mn></mrow></msub></mrow> <annotation>$$ {T}_1/{T}_2 $$</annotation></semantics></math> Myocardial Tissue Mapping at <math><semantics><mrow><mn>0</mn> <mo>.</mo> <mn>55</mn></mrow> <annotation>$$ 0.55 $$</annotation></semantics></math> T.

NMR in biomedicine·2026
Same author

Fully-Constrained Variable Projection for Water-Fat Models.

Magnetic resonance in medicine·2026
Same author

Contrast-free postoperative imaging of the pulmonary arteries: Intraindividual comparison of relaxation-enhanced angiography without contrast and triggering and time-resolved contrast-enhanced magnetic resonance angiography.

Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance·2026
Same author

Deep learning improves image quality in motion-robust and sedation-free pediatric brain MRI.

European radiology·2026
Same author

Correction: Enhancing SNR in MRI at 7T using wearable coils, dielectric resonators, and dipole antennas.

Magma (New York, N.Y.)·2026
Same author

Ultrafast deep learning super-resolution single-shot T2-weighted imaging for robust edema visualization in cardiovascular magnetic resonance.

Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance·2026
Same journal

Dependence of the Extra-Cellular Diffusion Coefficient on the Fractions of Neurites and Cell Bodies in Gray Matter.

Magnetic resonance in medicine·2026
Same journal

Triple-Pulse <sup>23</sup>Na MRI Sequence (TriNa) for Simultaneous Acquisition of Spin-Density-Weighted and Fluid-Attenuated Images.

Magnetic resonance in medicine·2026
Same journal

Evaluation of Phantom Doping Materials in Quantitative Susceptibility Mapping.

Magnetic resonance in medicine·2026
Same journal

Design of an 8-Channel Transmit 32-Channel Receive 11.7T Head Coil and Evaluation of SNR Gains.

Magnetic resonance in medicine·2026
Same journal

The Potential for Absolute Temperature Imaging Based on Brain Metabolites Using an FID-Shifting Approach in Gradient Echo Planar Spectroscopic Imaging (GREPSI).

Magnetic resonance in medicine·2026
Same journal

Prospective Head Motion Correction in T1- and T2-Weighted Long Echo Train Sequences Using Servo Navigation.

Magnetic resonance in medicine·2026
See all related articles
This summary is machine-generated.

A novel free-breathing MRI technique accurately maps abdominal fat fraction (PDFF) at high resolution. Phase corrections significantly improved image quality and reduced bias in liver and pancreas PDFF quantification.

Area of Science:

  • Magnetic Resonance Imaging (MRI)
  • Medical Physics
  • Radiology

Background:

  • Proton density fat fraction (PDFF) mapping is crucial for assessing liver and pancreatic diseases.
  • Existing MRI techniques often require breath-holding, limiting patient comfort and scan efficiency.
  • High-resolution, free-breathing abdominal PDFF mapping remains a challenge.

Purpose of the Study:

  • To develop and validate a phase-corrected, time-interleaved multi-echo gradient echo Cartesian acquisition with spiral profile ordering (TIMGRECASPR) for abdominal PDFF mapping.
  • To demonstrate the technique's flexibility and self-gating capabilities at high isotropic resolutions (3T).
  • To assess the accuracy and homogeneity of PDFF quantification in the liver and pancreas.

Main Methods:

  • Developed a methodological framework to correct phase errors from eddy currents and concomitant gradients in TIMGRECASPR.
Keywords:
Cartesian spiral profile ordering (CASPR)free‐breathingisotropic resolutionphase errorsproton density fat fraction (PDFF)time‐interleaved multi‐echo gradient echo

More Related Videos

Tracking the Mammary Architectural Features and Detecting Breast Cancer with Magnetic Resonance Diffusion Tensor Imaging
15:48

Tracking the Mammary Architectural Features and Detecting Breast Cancer with Magnetic Resonance Diffusion Tensor Imaging

Published on: December 15, 2014

Related Experiment Videos

Last Updated: Jun 18, 2026

Fat-Water Phantoms for Magnetic Resonance Imaging Validation: A Flexible and Scalable Protocol
07:59

Fat-Water Phantoms for Magnetic Resonance Imaging Validation: A Flexible and Scalable Protocol

Published on: September 7, 2018

Tracking the Mammary Architectural Features and Detecting Breast Cancer with Magnetic Resonance Diffusion Tensor Imaging
15:48

Tracking the Mammary Architectural Features and Detecting Breast Cancer with Magnetic Resonance Diffusion Tensor Imaging

Published on: December 15, 2014

  • Optimized sequence parameters using XCAT simulations and validated in phantoms and in vivo.
  • Compared liver and pancreatic PDFF, T2*, and homogeneity against a clinical Cartesian breath-hold technique in five healthy volunteers.

    • Main Results:

    • Phase corrections successfully mitigated peripheral PDFF bias, particularly at higher resolutions.
    • Liver PDFF maps showed improved homogeneity with accurate quantification (0.6% bias, 0.11% wSD).
    • Pancreatic boundaries were clearly visualized, yielding accurate PDFF maps (1.1% bias, 0.37% wSD).

    Conclusions:

    • The developed free-breathing TIMGRECASPR sequence is feasible for abdominal PDFF mapping at 3T.
    • Accounting for phase errors is essential for accurate, high-resolution PDFF quantification.
    • The technique offers sampling flexibility and inherent self-gating capabilities.