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In Vivo SiRNA Transfection and Gene Knockdown in Spinal Cord via Rapid Noninvasive Lumbar Intrathecal Injections in Mice
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In Vivo SiRNA Transfection and Gene Knockdown in Spinal Cord via Rapid Noninvasive Lumbar Intrathecal Injections in Mice

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International Pain and Spine Intervention Society Emergency Protocols: Intra-arterial Injection.

Nathaniel M Schuster1, Stephan Klessinger2, Patrick H Waring3

  • 1Center for Pain Medicine, Department of Anesthesiology, University of California San Diego Health System, La Jolla, CA, USA.

Interventional Pain Medicine
|June 19, 2026
PubMed
Summary

Inadvertent intra-arterial injection during spine procedures can cause severe neurological damage. This protocol outlines immediate steps to recognize and manage these critical events, improving patient outcomes.

Keywords:
EmergenciesEmergency protocolInterventional pain proceduresIntra-arterial injectionRisk mitigation

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