Related Experiment Videos

Independent double-checking of high-risk medications among hospitalized pediatric patients: a best practice

Reagan McMurtery1,2, Michelle Palokas1,2

  • 1School of Nursing, University of Mississippi Medical Center, Jackson, MS, USA.

Insights

Implementing evidence-based practices for independent double-checking of high-risk medications improved compliance by 7% in a pediatric unit. This initiative aimed to reduce medication errors in pediatric patients, who are more vulnerable to harm from such errors.

Area of Science:

  • Pediatric Patient Safety
  • Medication Error Reduction
  • Evidence-Based Practice Implementation

Background:

  • Pediatric patients face higher risks of medication errors due to weight-based dosing.
  • Adverse drug events are three times more common in children than adults.
  • A Mississippi pediatric unit reported four high-risk medication errors in 2023, representing 21% of all errors.

Purpose of the Study:

  • To enhance evidence-based practices for independent double-checking of high-risk medications.
  • To decrease medication errors within a pediatric inpatient setting.
  • To improve patient safety in pediatric care.

Main Methods:

  • Utilized the JBI Evidence Implementation Framework, PACES, and GRiP audit strategy.
  • Conducted baseline and follow-up audits assessing nine evidence-based practices.
  • Implemented targeted strategies to address identified compliance barriers.

Main Results:

  • Baseline compliance with evidence-based practices was 70%.
  • Key barriers included insufficient staff knowledge and unclear policies.
  • Post-implementation compliance increased to 77% after implementing education and policy revisions.

Conclusions:

  • Clinical audit effectively improved independent double-checking of high-risk medications.
  • Evidence implementation projects can enhance pediatric medication safety.
  • Sustained focus on best practices reduces pediatric medication errors.
Abstract

Related Concept Videos

Pharmacokinetics in Pediatric Patients: Drug Excretion01:26

Pharmacokinetics in Pediatric Patients: Drug Excretion

In pediatric medicine, understanding the renal function and drug elimination nuances is crucial for administering safe and effective treatments. Newborns, in particular, display markedly slower renal functions than adults, profoundly affecting how drugs are cleared from their bodies. This slower drug clearance requires clinicians to extend the dosing intervals for many medications to prevent drug accumulation and toxicity while ensuring therapeutic efficacy.One key area where these adjustments...
Pharmacokinetics in Pediatric Patients: Drug Distribution01:17

Pharmacokinetics in Pediatric Patients: Drug Distribution

Drug distribution in the pediatric population exhibits unique challenges and considerations due to the physiological differences between children, particularly neonates and infants, and adults. A crucial aspect of pediatric pharmacology is understanding how these differences impact the pharmacokinetics of various drugs, necessitating age-specific dosing strategies to ensure efficacy and safety.Neonates and infants have a higher total body water content, ~75%–90% of their body weight, compared...
Pharmaceutical Poisoning: Potential Scenarios01:26

Pharmaceutical Poisoning: Potential Scenarios

Pharmaceutical poisoning can occur through various channels, impacting an estimated 2 million hospitalized patients in the U.S. annually with serious adverse drug responses. These scenarios encompass both therapeutic uses, such as drug toxicity, where even standard dosages can lead to severe central nervous system depression, and non-therapeutic exposures, including accidental ingestion by children, and environmental and occupational exposures.Unintentional poisonings often involve exploratory...
Healthcare Associated Infections II: Preventive Measures01:22

Healthcare Associated Infections II: Preventive Measures

Essential infection prevention measures are based on the knowledge of the infection chain, the modes of transmission in healthcare settings, and the use of the best practices in all healthcare settings. Compulsory public reporting of healthcare-associated infection rates is needed to allow individuals and the community to make informed choices regarding selecting a healthcare facility.
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...
Pharmacokinetics in Pediatric Patients: Drug Metabolism01:24

Pharmacokinetics in Pediatric Patients: Drug Metabolism

In pediatric care, understanding the nuances of hepatic drug metabolism is crucial, as it significantly differs from that of adults. This divergence is primarily due to the developmental stage of drug-metabolizing enzymes, which affects how medications are processed in the body. In neonates, for instance, the activity of Phase I enzymes—critical for the initial breakdown of drugs—is markedly reduced, functioning at just 20–40% of the levels seen in adults. This reduction poses a challenge in...
Drug Dosing: Infants and Children01:29

Drug Dosing: Infants and Children

Pediatric patient dosages diverge from adults due to disparities in body surface area, total body water, and extracellular fluid per kilogram of body weight. The dosing regimen considers the variations in pharmacokinetics and pharmacology across distinct age groups, encompassing preterm newborns, infants, young children, older children, and adolescents. Calculation of pediatric patient doses is predicated on determining body surface area, which exhibits a superior correlation with the child's...