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Allergic Reactions

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Desensitization and Tachyphylaxis

Desensitization and Tachyphylaxis

Tachyphylaxis is described as a rapid decrease in response to a drug after repeated or continuous administration of the same drug dose. It is a phenomenon where the body becomes less responsive to a particular substance or intervention over time, requiring higher doses or stronger interventions to achieve the same effect. It results from adaptive changes in the body's receptors, signaling pathways, or physiological processes that occur in response to prolonged exposure to a stimulus.
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Updated: Jun 21, 2026

A Component-resolved Diagnostic Approach for a Study on Grass Pollen Allergens in Chinese Southerners with Allergic Rhinitis and/or Asthma

A Component-resolved Diagnostic Approach for a Study on Grass Pollen Allergens in Chinese Southerners with Allergic Rhinitis and/or Asthma

Published on: June 4, 2017

SCIT and SLIT: two different paths to grass-pollen desensitization

Sofia Sirvent¹, Natalia Cuervo¹, Oscar Palomares¹

¹Department of Biochemistry and Molecular Biology, School of Chemistry, Complutense University of Madrid, Madrid, Spain.

The Journal of Allergy and Clinical Immunology

|June 19, 2026

Summary

No abstract available in PubMed .

Keywords:

CRTH2 TH2A cells allergen immunotherapy subcutaneous immunotherapy sublingual immunotherapy

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