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Related Concept Videos

Skin Diseases and Disorders01:23

Skin Diseases and Disorders

Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
Acne Infection01:27

Acne Infection

Acne is a multifactorial skin condition primarily affecting adolescents and young adults, with a global prevalence estimated to exceed 75% in this demographic. The condition is characterized by the formation of comedones (blackheads and whiteheads), papules, pustules, nodules, and, in severe cases, cysts, particularly in areas rich in sebaceous glands such as the face, neck, chest, and back. The pathogenesis involves increased sebum production, follicular hyperkeratinization, colonization by...
Factors Affecting the Risk of Infection01:26

Factors Affecting the Risk of Infection

The hosts' susceptibility to infection depends on several factors. The integrity of the skin and mucous membranes helps protect the body against microbial attacks. When the skin is altered, the chance of infection, limb loss, and even death increases.
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin create...
Skin Cancer01:30

Skin Cancer

Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
Changes in Skin Color: Clinical Perspectives01:14

Changes in Skin Color: Clinical Perspectives

The first thing a clinician sees is the skin, so the examination of the skin should be part of any thorough physical examination. Most skin disorders are relatively benign, but a few, including melanomas, can be fatal if untreated. A couple of the more noticeable disorders, albinism and vitiligo, affect the appearance of the skin and its accessory organs.
Albinism
Albinism is a genetic disorder that affects (completely or partially) the coloring of skin, hair, and eyes. The defect is primarily...
Staphylococcal Skin Infections01:29

Staphylococcal Skin Infections

Staphylococcus aureus is a Gram-positive coccus that resides harmlessly on the skin and mucous membranes of healthy individuals. When the skin barrier is breached, it can shift from a commensal to an opportunistic pathogen. This transition is facilitated by surface adhesins, such as clumping factor B and S. aureus surface protein G (SasG), which bind to structural proteins, including loricrin and cytokeratin, in the damaged epidermis. Protein A, another key factor, binds the Fc region of...

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Related Experiment Video

Updated: Jun 23, 2026

Resolving Water, Proteins, and Lipids from In Vivo Confocal Raman Spectra of Stratum Corneum through a Chemometric Approach
09:32

Resolving Water, Proteins, and Lipids from In Vivo Confocal Raman Spectra of Stratum Corneum through a Chemometric Approach

Published on: September 26, 2019

Risk Factors Associated With Major Skin Diseases: A Cross-Sectional Study From Bangladesh.

Md Abrar Ashfaq Khan1,2, Md Rashed Babu2, Mohammad Ohid Ullah2

  • 1Department of Data Science and Statistics, Oregon State University, Corvallis, Oregon, USA, oregon.gov.

Global Health, Epidemiology and Genomics
|June 20, 2026
PubMed
Summary

This study in Bangladesh found that a family history of skin disease increases the risk of fungal infections, and environmental factors are linked to acne vulgaris. These findings highlight the need for targeted interventions for common skin conditions.

Keywords:
Bangladeshacne vulgarisenvironmental factorsfungal infectionheritable factorsprincipal component analysisskin disease

Related Experiment Videos

Last Updated: Jun 23, 2026

Resolving Water, Proteins, and Lipids from In Vivo Confocal Raman Spectra of Stratum Corneum through a Chemometric Approach
09:32

Resolving Water, Proteins, and Lipids from In Vivo Confocal Raman Spectra of Stratum Corneum through a Chemometric Approach

Published on: September 26, 2019

Area of Science:

  • Dermatology and Public Health in Bangladesh
  • Epidemiological research methods
  • Risk factor analysis for skin diseases

Background:

  • Skin diseases are a significant public health concern in Bangladesh, impacting all age groups.
  • Understanding the specific risk factors is crucial for effective prevention and management.

Purpose of the Study:

  • To identify lifestyle, environmental, food-related, and heritable risk factors for skin diseases in Bangladesh.
  • To analyze the associations between these factors and specific dermatological conditions.

Main Methods:

  • A cross-sectional study involving 788 respondents across three divisions in Bangladesh.
  • Data collection via structured questionnaires on skin disease status and potential risk factors.
  • Statistical analysis using Principal Component Analysis (PCA) and Principal Component Logistic Regression (PCLR) with goodness-of-fit and sensitivity analyses.

Main Results:

  • 61.80% of respondents reported skin diseases, with atopic dermatitis, fungal infections, and acne vulgaris being most common.
  • Heritable factors were significantly associated with fungal infections (adjusted OR: 1.37).
  • Environmental factors were significantly associated with acne vulgaris (adjusted OR: 1.32).

Conclusions:

  • Family history is a key determinant for fungal infections, while environmental exposures influence acne vulgaris in Bangladesh.
  • The study emphasizes the importance of rigorous statistical validation in observational research.
  • Findings support targeted interventions for fungal infections and environmental mitigation for acne vulgaris.