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Testing a Web-Based Parent-Focused HIV Prevention Intervention for Gay and Bisexual Adolescents: Protocol for a
David M Huebner1, Brian Rw Baucom2, Stephanie Micucci3
1Department of Prevention and Community Health, Milken Institute School of Public Health, George Washington University, Washington, DC, United States.
JMIR Research Protocols
|June 22, 2026
Summary
Parents and Adolescent Talking About Healthy Sexuality (PATHS) is a web-based intervention designed to improve sexual health outcomes for gay and bisexual adolescents (GBA) by enhancing parent communication. This study is evaluating its efficacy in reducing HIV sexual risk behaviors among GBA.
Area of Science:
- Adolescent Health
- Public Health
- HIV Prevention
Background:
- Gay and bisexual adolescents (GBA) account for 79% of HIV infections among US teenagers.
- Few interventions effectively reduce sexual risk among GBA.
- Parent communication about sex is linked to adolescent sexual risk, with interventions showing success in heterosexual samples.
Purpose of the Study:
- To test the efficacy of the Parents and Adolescent Talking About Healthy Sexuality (PATHS) web-based intervention in improving sexual health outcomes for GBA aged 14-19.
- To assess the sustained effects of PATHS at 12 months post-intervention.
- To examine if intervention effects are mediated by specific parent behaviors.
Main Methods:
- 350 parents of GBA recruited online and randomized to PATHS or an active control.
- PATHS is a self-paced, automated, single-session web-based intervention.
- Participants assessed every 3 months for 1 year; primary outcomes at 6 months.
Main Results:
- Enrollment of 393 parent-GBA dyads completed September 2025.
- Study activities projected completion by November 2026.
- Data analysis and trial results are forthcoming in Q1 2027.
Conclusions:
- If efficacious, PATHS will be a pioneering HIV prevention intervention for GBA.
- PATHS offers a complementary approach by engaging parents, reaching GBA who may not engage with other interventions.
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