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Updated: Jun 24, 2026
08:51
Atomic Force Microscopy Combined with Infrared Spectroscopy as a Tool to Probe Single Bacterium Chemistry
Published on: September 15, 2020
[Bacteremias due to multidrug-resistant microorganisms].
Agostina Bonilla1,2, Carolina J Duffaut Anun1,2, Emanuel Ponce Figueroa1,2
1Instituto Universitario de Ciencias Biomédicas de Córdoba (IUCBC), Córdoba, Argentina.
Medicina
|June 22, 2026
Summary
Multidrug-resistant bacteria (MDRB) caused 38.4% of bacteremias, leading to higher mortality. Key risk factors for MDRB bloodstream infections include recent hospitalization, ICU admission, prior antibiotic use, and diabetes mellitus.
Area of Science:
- Infectious Diseases
- Clinical Microbiology
- Epidemiology
Background:
- Multidrug-resistant bacteria (MDRB) bacteremias pose a significant global health challenge.
- These infections are linked to increased morbidity, mortality, and extended hospital stays.
Purpose of the Study:
- To determine the incidence, clinical features, and risk factors of MDRB bacteremia in hospitalized adults.
- To analyze mortality rates associated with MDRB bacteremia.
Main Methods:
- Retrospective, observational cohort study.
- Analysis of blood cultures from adult patients between January 2020 and February 2021.
- Multivariate analysis to identify independent risk factors for MDRB bacteremia.
Main Results:
- MDRB accounted for 38.4% of 403 bacteremia episodes.
- Thirty-day mortality was significantly higher in MDRB cases (33.5%) versus non-MDRB cases (21.8%).
- Independent risk factors identified: hospitalization >48h, recent ICU admission, prior antibiotic use, and diabetes mellitus.
Conclusions:
- MDRB bacteremia represents a substantial portion of bloodstream infections with elevated mortality.
- Identifying specific risk factors is crucial for optimizing diagnostic and therapeutic strategies.
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