Related Experiment Video
Updated: Jun 24, 2026

08:28
Single-molecule Manipulation of G-quadruplexes by Magnetic Tweezers
Published on: September 19, 2017
Direct visualization and functional characterization of Gar2Nucleolin-G-quadruplex interactions
Ajay Kumar1, Nasim Sabouri1,2
1Department of Medical Biochemistry and Biophysics, Umeå 90187, Sweden. nasim.sabouri@umu.se.
Abstract:
We demonstrate that the conserved nucleolar protein Gar2Nucleolin binds and destabilizes G-quadruplexes, identifying a new regulator of G4 dynamics in ribosome biogenesis and genome organization.

