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Case Report: Post-transplant lymphoproliferative disorder mimicking Baló's concentric sclerosis
Xiaofeng Xiong1, Ting Zhang2, Yu Li3
1Department of Neurology, Shenzhen People's Hospital, The Second Clinical Medical College, Jinan University, Shenzhen, China.
Frontiers in Oncology
|June 24, 2026
Summary
Post-Transplant Lymphoproliferative Disorder (PTLD) can affect the central nervous system, mimicking other conditions. Early diagnosis of PCNS-PTLD is crucial for appropriate treatment and improved outcomes.
Area of Science:
- Neurology
- Oncology
- Immunology
Background:
- Post-Transplant Lymphoproliferative Disorder (PTLD) is a serious complication following transplantation, arising from immunosuppression-induced lymphoid or plasma cell malignancy.
- PTLD can affect various organs, including the central nervous system (CNS), often presenting with a poor prognosis.
- Distinguishing PTLD in the CNS from other neurological conditions is challenging due to overlapping clinical and imaging features.
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